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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 377 - 383 (7page)
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초록· 키워드
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Severe acute respiratory syndrome-coronavirus 2 (SARSCoV- 2) is a novel virus that causes coronavirus disease 2019 (COVID-19). To understand the identity, functional characteristics and therapeutic targets of the virus and the diseases, appropriate infection models that recapitulate the in vivo pathophysiology of the viral infection are necessary. This article reviews the various infection models, including Vero cells, human cell lines, organoids, and animal models, and discusses their advantages and disadvantages. This knowledge will be helpful for establishing an efficient system for defense against emerging infectious diseases.
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참고문헌 (69)
참고문헌 신청
Ammerman, N. C. / 2008 / Growth and maintenance of Vero cell lines / Curr. Protoc. Microbiol. Appendix 4:4E
Bao, L. / 2020 / The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice / Nature 583:830~833
Barretina, J. / 2012 / The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity / Nature 483:603~607
Beigel, J. H. / 2020 / Remdesivir for the treatment of Covid-19 - final report / N. Engl. J. Med 383:1813~1826
Broutier, L. / 2016 / Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation / Nat. Protoc 11:1724~1743
Bao, L. / 2020 / The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice / Nature 583:830~833
Barretina, J. / 2012 / The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity / Nature 483:603~607
Beigel, J. H. / 2020 / Remdesivir for the treatment of Covid-19 - final report / N. Engl. J. Med 383:1813~1826
Broutier, L. / 2016 / Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation / Nat. Protoc 11:1724~1743
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