지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.98 No.5
- 발행연도
- 2020.5
- 수록면
- 224 - 234 (11page)
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초록· 키워드
오류제보하기
Purpose: To evaluate the safety and effectiveness of an enhanced recovery after surgery (ERAS) programme after curative liver resection in cirrhotic hepatocellular carcinoma (HCC) patients.
Methods: One hundred sixty-two patients were enrolled in the study; 80 patients whose data were collected prospectively were assigned to the ERAS group, and 82 patients whose data were collected retrospectively were assigned to the control group. Preoperative clinicopathologic factors, surgical factors, and postoperative outcomes of the 2 groups were compared. Logistic regression was applied to explore potential predictors of hospital stay and morbidity.
Results: The postoperative hospital stay, postoperative complication rate, and recovery of liver function on postoperative day 5 seemed to be better in the ERAS group. The composition of complications was different in the 2 groups; pleural effusion and postoperative ascites were more common in the control group, and indocyanine green retention at 15 minutes, operation time, preoperative alanine aminotransferase, and number of liver segmentectomies were associated with postoperative complications rather than ERAS intervention.
Conclusion: The ERAS programme is safe and effective for HCC patients with chronic liver disease undergoing hepatectomy, but it seems that surgical factors, such as operation type, have a greater impact on morbidity than other factors. Operative characteristics such as the method of blood loss control and the volume of liver resection should be augmented into ERAS protocol of hepatectomy.
Methods: One hundred sixty-two patients were enrolled in the study; 80 patients whose data were collected prospectively were assigned to the ERAS group, and 82 patients whose data were collected retrospectively were assigned to the control group. Preoperative clinicopathologic factors, surgical factors, and postoperative outcomes of the 2 groups were compared. Logistic regression was applied to explore potential predictors of hospital stay and morbidity.
Results: The postoperative hospital stay, postoperative complication rate, and recovery of liver function on postoperative day 5 seemed to be better in the ERAS group. The composition of complications was different in the 2 groups; pleural effusion and postoperative ascites were more common in the control group, and indocyanine green retention at 15 minutes, operation time, preoperative alanine aminotransferase, and number of liver segmentectomies were associated with postoperative complications rather than ERAS intervention.
Conclusion: The ERAS programme is safe and effective for HCC patients with chronic liver disease undergoing hepatectomy, but it seems that surgical factors, such as operation type, have a greater impact on morbidity than other factors. Operative characteristics such as the method of blood loss control and the volume of liver resection should be augmented into ERAS protocol of hepatectomy.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (30)
참고문헌 신청
Heimbach JK / 2018 / AASLD guidelines for the treatment of hepatocellular carcinoma / Hepatology 67:358~380
Takamoto T / 2014 / Applicability of enhanced recovery program for advanced liver surgery / World J Surg 38:2676~2682
Page AJ / 2012 / Perioperat ive management of hepatic resection / J Gastrointest Oncol 3:19~27
Sasaki K / 2017 / Effect of background liver cirrhosis on outcomes of hepatectomy for hepatocellular carcinoma / JAMA Surg 152:e165059
Kamiyama T / 2010 / Perioperative management of hepatic resection toward zero mortality and morbidity : analysis of 793 consecutive cases in a single institution / J Am Coll Surg 211:443~449
Takamoto T / 2014 / Applicability of enhanced recovery program for advanced liver surgery / World J Surg 38:2676~2682
Page AJ / 2012 / Perioperat ive management of hepatic resection / J Gastrointest Oncol 3:19~27
Sasaki K / 2017 / Effect of background liver cirrhosis on outcomes of hepatectomy for hepatocellular carcinoma / JAMA Surg 152:e165059
Kamiyama T / 2010 / Perioperative management of hepatic resection toward zero mortality and morbidity : analysis of 793 consecutive cases in a single institution / J Am Coll Surg 211:443~449
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