지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.12
- 수록면
- 93 - 99 (7page)
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초록· 키워드
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Purpose: The objective of the current study was to compare surgical outcomes and prognosis based on the longitudinal location of stomach tumors in patients undergoing curative treatment. The specific focus was on the prognosis for adenocarcinomas in the proximal upper-third of the stomach, excluding tumors in the esophagogastric junction (EGJ).
Methods: Data from patients who underwent curative treatment for gastric adenocarcinoma between 2000 and 2010 at a single institution were analyzed retrospectively. Excluding tumors of EGJ origin, data from 797 patients were reviewed—686 with distal gastric cancer and 111 with proximal gastric cancer. Clinicopathology features, tumor stage, surgical outcomes, recurrence, and survival were compared between the groups.
Results: Gastric cancer recurred in 136 of the patients (17.1%). Although differences were detected between proximal and distal cancer patients in the prevalence in males versus females (74.8% vs. 63.4%, P=0.020) and in undifferentiated histology (60.4% vs. 47.7%, P=0.013), the prognosis for proximal gastric cancer did not differ from distal gastric cancer. The overall 5-year disease-free survival rate was 84.9% and 81.4% in proximal and distal cancer patients, respectively (P=0.389).
Conclusion: The prognosis of proximal cancer, excluding tumors of EGJ origin, did not differ from the prognosis of more distal gastric cancer. Clarifying the prognosis of proximal gastric cancer will require the large-scale comparison of an organized, multi-institution database.
Methods: Data from patients who underwent curative treatment for gastric adenocarcinoma between 2000 and 2010 at a single institution were analyzed retrospectively. Excluding tumors of EGJ origin, data from 797 patients were reviewed—686 with distal gastric cancer and 111 with proximal gastric cancer. Clinicopathology features, tumor stage, surgical outcomes, recurrence, and survival were compared between the groups.
Results: Gastric cancer recurred in 136 of the patients (17.1%). Although differences were detected between proximal and distal cancer patients in the prevalence in males versus females (74.8% vs. 63.4%, P=0.020) and in undifferentiated histology (60.4% vs. 47.7%, P=0.013), the prognosis for proximal gastric cancer did not differ from distal gastric cancer. The overall 5-year disease-free survival rate was 84.9% and 81.4% in proximal and distal cancer patients, respectively (P=0.389).
Conclusion: The prognosis of proximal cancer, excluding tumors of EGJ origin, did not differ from the prognosis of more distal gastric cancer. Clarifying the prognosis of proximal gastric cancer will require the large-scale comparison of an organized, multi-institution database.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (18)
참고문헌 신청
Colquhoun A / 2015 / Global patterns of cardia and non-cardia gastric cancer incidence in 2012 / Gut 64:1881~1888
엄방울 / 2016 / Korean Gastric Cancer Association Nationwide Survey on Gastric Cancer in 2014 / Journal of Gastric Cancer 16(3):131~140
Rüdiger Siewert J / 2000 / Adenocarcinoma of the esophagogastric junction: results of surgical therapy based on anatomical/topographic classification in 1,002 consecutive patients / Ann Surg 232:353~361
Kajiyama Y / 1997 / Prognostic factors in adenocarcinoma of the gastric cardia: pathologic stage analysis and multivariate regression analysis / J Clin Oncol 15:2015~2021
Deans C / 2011 / Cancer of the gastric cardia is rising in incidence in an Asian population and is associated with adverse outcome / World J Surg 35:617~624
엄방울 / 2016 / Korean Gastric Cancer Association Nationwide Survey on Gastric Cancer in 2014 / Journal of Gastric Cancer 16(3):131~140
Rüdiger Siewert J / 2000 / Adenocarcinoma of the esophagogastric junction: results of surgical therapy based on anatomical/topographic classification in 1,002 consecutive patients / Ann Surg 232:353~361
Kajiyama Y / 1997 / Prognostic factors in adenocarcinoma of the gastric cardia: pathologic stage analysis and multivariate regression analysis / J Clin Oncol 15:2015~2021
Deans C / 2011 / Cancer of the gastric cardia is rising in incidence in an Asian population and is associated with adverse outcome / World J Surg 35:617~624
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