Clinical significance and prognostic value of C-reactive protein/albumin ratio in gastric cancer

Qian Yu; Ke-zhi Li; Yan-jun Fu; Yanping Tang; Xin-qiang Liang; Zhi-qing Liang; Ji-hong Bai

Clinical significance and prognostic value of C-reactive protein/albumin ratio in gastric cancer

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Type: Academic journal

Author: Qian Yu (Affiliated Hospital of Guilin Medical University) Ke-zhi Li (Guangxi Medical University Cancer Hospital) Yan-jun Fu (Affiliated Hospital of Guilin Medical University) Yanping Tang (Guangxi Medical University Cancer Hospital) Xin-qiang Liang (Guangxi Medical University Cancer Hospital) Zhi-qing Liang (Affiliated Hospital of Guilin Medical University)

Journal: The Korean Surgical Society Annals of Surgical Treatment and Research Vol.100 No.6 KCI Accredited Journals SCIE

Published: 2021.6

Pages: 338 - 346 (9page)

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Clinical significance and prognostic value of C-reactive protein/albumin ratio in gastric cancer

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Purpose: This study was aimed to evaluate the clinical significance and prognostic value of CRP/albumin ratio (CAR) in patients with gastric cancer.
Methods: The data of 205 gastric cancer patients who underwent surgery was analyzed retrospectively. The association of CAR with the clinical features and prognostic value in gastric cancer was analyzed. The data of this study was combined with previous studies to further determine the prognostic value of CAR in patients with gastric cancer using a meta-analysis method.
Results: Cox analysis revealed that preoperative CAR was an independent prognosis indicator in patients with gastric cancer. High expression of CAR indicated a shorter survival time than in those with lower expression. CAR has a higher prognostic value in the 1-, 3-, and 5-year overall survival in patients with gastric cancer. CAR showed significant difference regarding the gastric cancer patients’ age, M stage, and clinical stage. The discriminate value of CAR in M stage of gastric cancer was high (area under the curve, 0.809). A meta-analysis combining previous data and our data showed that preoperative CAR demonstrated a significant association with the overall survival of patients with gastric cancer.
Conclusion: This study demonstrated that preoperative CAR could serve as an important prognostic indicator in patients with gastric cancer.

#C-reactive protein/albumin ratio #Preoperative #Prognosis #Stomach neoplasms

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