지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.12
- 수록면
- 56 - 60 (5page)
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초록· 키워드
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Purpose: The prognosis of periampullary cancer varies with its origin and early diagnosis influences outcome. Endoscopic ultrasound, computed tomography, fine needle aspiration, and fluorodeoxyglucose-positron emission tomography/computed tomography (18FDG-PET/CT) are helpful for diagnosis. This study evaluates the diagnostic efficacy of 18FDG-PET for preoperative periampullary tumors.
Methods: A series of 100 patients undergoing 18FDG-PET/CT before surgical resection of periampullary tumors between March 2011 and February 2019 were enrolled. Maximum standardized uptake value (SUVmax) and carbohydrate antigen 19-9 (CA19-9) levels were compared with pathohistological confirmation of periampullary tumors.
Results: The SUVmax and uptake range varied with the origin of the periampullary tumors. The SUVmax was not available for 17 of the 42 pancreas tumors, three of 30 common bile duct tumors, and four of 18 ampulla of Vater tumors. The median SUVmax was 0.0 in benign tumors and 5.05 in malignant tumors. The mean SUVmax was 4.1±5.6 in pancreatic tumors, 3.9±2.4 in ampulla of Vater, and 6.0±3.7 in common bile duct. The SUVmax was higher in common bile duct tumors than others. CA19-9 level was of diagnostic value in pancreatic tumor patients. The median CA19-9 levels were 7.64 U/mL (range, 2.71-45.05 U/mL) in benign tumors and 91.97 U/mL (range, 26.91-276.60 U/mL) in cancers patients.
Conclusion: Preoperative SUVmax and CA19-9 level were of diagnostic value for periampullary tumors originating in the pancreas.
Methods: A series of 100 patients undergoing 18FDG-PET/CT before surgical resection of periampullary tumors between March 2011 and February 2019 were enrolled. Maximum standardized uptake value (SUVmax) and carbohydrate antigen 19-9 (CA19-9) levels were compared with pathohistological confirmation of periampullary tumors.
Results: The SUVmax and uptake range varied with the origin of the periampullary tumors. The SUVmax was not available for 17 of the 42 pancreas tumors, three of 30 common bile duct tumors, and four of 18 ampulla of Vater tumors. The median SUVmax was 0.0 in benign tumors and 5.05 in malignant tumors. The mean SUVmax was 4.1±5.6 in pancreatic tumors, 3.9±2.4 in ampulla of Vater, and 6.0±3.7 in common bile duct. The SUVmax was higher in common bile duct tumors than others. CA19-9 level was of diagnostic value in pancreatic tumor patients. The median CA19-9 levels were 7.64 U/mL (range, 2.71-45.05 U/mL) in benign tumors and 91.97 U/mL (range, 26.91-276.60 U/mL) in cancers patients.
Conclusion: Preoperative SUVmax and CA19-9 level were of diagnostic value for periampullary tumors originating in the pancreas.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (21)
참고문헌 신청
Nasr Shaban EAI / 2016 / Added value of 18-F-FDG-PET/CT in patients with pancreatic cancer: initial observation / Egypt J Radiol Nucl Med 47:1275~1282
정규원 / 2018 / Prediction of Cancer Incidence and Mortality in Korea, 2018 / Cancer Research and Treatment 50(2):317~323
Pimiento JM / 2016 / Metabolic activity by 18F-FDG-PET/CT Is prognostic for stage I and II pancreatic cancer / Clin Nucl Med 41:177~181
Im HJ / 2016 / Prognostic value of metabolic and volumetric parameters of preoperative FDG-PET/CT in patients with resectable pancreatic cancer / Medicine (Baltimore) 95:e3686
Chirindel A / 2015 / Prognostic value of FDG PET/CT-Derived parameters in pancreatic adenocarcinoma at initial PET/CT staging / AJR Am J Roentgenol 204:1093~1099
정규원 / 2018 / Prediction of Cancer Incidence and Mortality in Korea, 2018 / Cancer Research and Treatment 50(2):317~323
Pimiento JM / 2016 / Metabolic activity by 18F-FDG-PET/CT Is prognostic for stage I and II pancreatic cancer / Clin Nucl Med 41:177~181
Im HJ / 2016 / Prognostic value of metabolic and volumetric parameters of preoperative FDG-PET/CT in patients with resectable pancreatic cancer / Medicine (Baltimore) 95:e3686
Chirindel A / 2015 / Prognostic value of FDG PET/CT-Derived parameters in pancreatic adenocarcinoma at initial PET/CT staging / AJR Am J Roentgenol 204:1093~1099
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