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논문 기본 정보

자료유형
학술저널
저자정보
권대근 (선문대학교) 송영주 (선문대학교)
저널정보
한국체육과학회 한국체육과학회지 한국체육과학회지 제28권 제6호 (자연과학 편)
발행연도
2019.12
수록면
1,005 - 1,017 (13page)
DOI
10.35159/kjss.2019.12.28.6.1005

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초록· 키워드

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This study was investigated to examine the effect of bidirectional isometric exercise on muscle atrophy of rats. 6 weeks-aged rats were randomly divided into 6 groups; control group(CG, n=8), 7 days passive recovery group (PR7, n=8), 7 days active recovery group(AR7, n=8), 14 days passive recovery group(PR14, n=8), 14 days active recovery group(AR14, n=8). All rats were casted left hindlimb for 7days. The rats of acive recovery groups were conducted to bidirectional isometric exercise for 10reps/1set, 10sets for 1week or 2weeks. In the results, soleus muscle weight of AR14 group was significantly increased compared to AR7 group. p-Akt protein expression and p-Akt/Akt of PR14 and AR14 was significantly increased compared to PR7 and AR7 group, respectively. In addition, Atrogin-1 protein expression of AR7 and AR14 was significantly decreased compared to PR7 and PR14 group, respectively. on the contrary to this, p-4EBP pretein expression of AR14 was significantly increased compared to AR7 and p-4EBP1/ 4EBP1 of AR14 was significantly increased compared to AR7 and PR14. From these results, bidirectional isometric exercise ameliorate skeletal muscle atrophy of rats via activation of Akt-mTOR pathway and inactivation of Fbx32 protein expression.

목차

Abstract
Ⅰ. 서론
Ⅱ. 연구방법
Ⅲ. 결과
Ⅳ. 논의
Ⅴ. 결론
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