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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Background: Although a growing number of guidelines and clinical researches are available for immunosuppressive treatment of post-transplantation, there is no clinical practice guideline for the care of kidney transplant recipients in Korea. Selection of a researchable question is the most important step in conducting qualified guideline development. Thus, we aimed to formulate key questions for Korean guideline to aid clinical decision-making for immunosuppressive treatment. Methods: Based on previous published guidelines review, a first survey was constructed with 29 questions in the range of immunosuppressive treatments. The experts were asked to rate the clinical importance of the question using a 5-point Likert scale. The questions reached 60% or more from the first survey and additional new questions were included in the second survey. In analyzing the responses to items rated on the 9-point scale, consensus agreement on each question was defined as 75% or more of experts rating 7 to 9. Results: In the first survey, 50 experts were included. Among the 29 questions, 27 were derived to get 60% or more importance and 3 new questions were additionally identified. Through the second survey, 9 questions were selected that experts reached consensus on 75% and over of the options. Finally, we developed key questions using PICO (patient, intervention, comparison, and outcome) methodology. Conclusion: The experts reached a high level of consensus on many of key questions in the survey. Final key questions provide direction for developing clinical practice guideline in the immunosuppressive treatment of transplantation.
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참고문헌 (19)
참고문헌 신청
Port FK / 1993 / Comparison of survival probabilities for dialysis patients vs cadaveric renal transplant recipients / JAMA 270(11):1339~1343
Kim SI / 2010 / A renal transplantation and hemodialysis cost-utility analysis in patients with end-stage renal disease / J Korean Soc Transplant 24(3):173~181
Korean Network for Organ Sharing / Annual report of the transplant 2017 / Korean Network for Organ Sharing
Kim SH / 2017 / Economic burden of chronic kidney disease in Korea using national sample cohort / J Nephrol 30(6):787~793
Legendre C / 2014 / Factors influencing long-term outcome after kidney transplantation / Transpl Int 27(1):19~27
Kim SI / 2010 / A renal transplantation and hemodialysis cost-utility analysis in patients with end-stage renal disease / J Korean Soc Transplant 24(3):173~181
Korean Network for Organ Sharing / Annual report of the transplant 2017 / Korean Network for Organ Sharing
Kim SH / 2017 / Economic burden of chronic kidney disease in Korea using national sample cohort / J Nephrol 30(6):787~793
Legendre C / 2014 / Factors influencing long-term outcome after kidney transplantation / Transpl Int 27(1):19~27
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