지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Background: Light-emitting diodes curing unit (LCU), which emit blue light, is used for polymerization of composite resins in many dentistry. Although the use of LCU for light-cured composite resin polymerization is considered safe, it is still controversial whether it can directly or indirectly have harmful biological influences on oral tissues. The aim of this study was to elucidate the biological effects of LCU in wavelengths ranging from 440 to 490 nm, on the cell viability and secretion of inflammatory cytokines in MDPC-23 odontoblastic cells and inflammatory-induced MDPC-23 cells by lipopolysaccharide (LPS). Methods: The MTT assay and observation using microscope were performed on MDPC-23 cells to investigate the cell viability and cytotoxic effects on LCU irradiation. Results: MDPC-23 cells and LPS stimulated MDPC-23 cells were found to have no effects on cell viability and cell morphology in the LCU irradiation. Nitric oxide (NO) and prostaglandin E2 which are the pro-inflammatory mediators, and interleukin-1 and tumor necrosis factor- (TNF-) which are the proinflammatory cytokines were significantly increased in MCPD-23 cells after LCU irradiation as time increased in comparison with the control. LCU irradiation has the potential to induce inflammation or biological damages in normal dental tissues, including MDPC-23 cells. Conclusion: Therefore, it is necessary to limit the use of LCU except for the appropriate dose and irradiation time. In addition, LCU irradiation of inflammatory-induced MDPC-23 cells by LPS was reduced the secretion of NO compared to the LPS alone treatment group and was significantly reduced the secretion of TNF- in all the time groups. Therefore, LCU application in LPS stimulated MDPC-23 odontoblastic cells has a photodynamic therapy like effect as well as inflammation relief.
목차
등록된 정보가 없습니다.
참고문헌 (35)
참고문헌 신청
Wataha JC / 2003 / In vitro biological response to core and flowable dental restorative materials / Dent Mater 19:25~31
Larry J. Oesterle / 2001 / Rapid curing of bonding composite with a xenon plasma arc light / American Journal of Orthodontics and Dentofacial Orthopedics 119(6):610~616
Arndt Klocke / 2002 / Plasma arc curing lights for orthodontic bonding / American Journal of Orthodontics and Dentofacial Orthopedics 122(6):643~648
Yalcin M / 2016 / The effect of light curing units on proliferation and senescence of human dental pulp mesenchymal stem cells / Int J Dent Sci Res 4:10~16
Aguiar FH / 2007 / Effect of light curing modes and light curing time on the microhardness of a hybrid composite resin / J Contemp Dent Pract 8:1~8
Larry J. Oesterle / 2001 / Rapid curing of bonding composite with a xenon plasma arc light / American Journal of Orthodontics and Dentofacial Orthopedics 119(6):610~616
Arndt Klocke / 2002 / Plasma arc curing lights for orthodontic bonding / American Journal of Orthodontics and Dentofacial Orthopedics 122(6):643~648
Yalcin M / 2016 / The effect of light curing units on proliferation and senescence of human dental pulp mesenchymal stem cells / Int J Dent Sci Res 4:10~16
Aguiar FH / 2007 / Effect of light curing modes and light curing time on the microhardness of a hybrid composite resin / J Contemp Dent Pract 8:1~8
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Effect of Resveratrol on Cell Differentiation and Mineralization in Cultured Odontoblasts
International Journal of Oral Biology
2018 .01
-
Effect of Metformin on Cell Growth and Differentiation in Cultured Odontoblasts
International Journal of Oral Biology
2017 .01
-
승마추출물이 MDPC-23세포의 분화에 미치는 영향
한국치위생학회지
2017 .06
-
MicroRNA-27 Promotes Odontoblast Differentiation via Wnt1 Signaling
International Journal of Oral Biology
2015 .01
-
Inflammatory Effect of Light-Emitting Diodes Curing Light Irradiation on Raw264.7 Macrophage
치위생과학회지
2019 .01
-
In vitro investigation of the antibacterial and anti-inflammatory effects of LED irradiation
Journal of Periodontal & Implant Science
2023 .04
-
Immune Correlates of Resistance to Trichinella spiralis Reinfection in Mice
Parasites, Hosts and Diseases
2016 .10
-
Clonal Expansion of Allergen-specific CD4+ T Cell in the Lung in the Absence of Lymph Nodes
Immune Network
2017 .06
-
Cell viability analysis
대한견주관절의학회 학술대회논문집
2015 .04
-
Pretreatment of Low-Dose and Super-Low-Dose LPS on the Production of In Vitro LPS-Induced Inflammatory Mediators
Toxicological Research
2018 .01
-
체외에서 배양된 구강 내 정상세포에 불화나트륨이 미치는 영향
한국치위생학회지
2016 .01
-
Regulation of Th2 Cell Immunity by Dendritic Cells
Immune Network
2016 .02
-
Anti-inflammatory Effects of Complex Extract including Eucommia ulmoides in LPS-induced RAW 264.7 Cells
대한침구의학회지
2019 .01
-
Heterogeneity of Islet Cells during Embryogenesis and Differentiation
Diabetes and Metabolism Journal
2023 .03
-
IL-17-Producing Cells in Tumor Immunity: Friends or Foes?
Immune Network
2020 .02
-
Unusual Suspects in the Development of Obesity- Induced Inflammation and Insulin Resistance: NK cells, iNKT cells, and ILCs
Diabetes and Metabolism Journal
2017 .01
-
선학초(仙鶴草)추출물의 대식세포에서의 LPS-유도 염증반응에 대한 효능 연구
대한본초학회지(본초분과학회지)
2016 .01
-
Research on Epstein-Barr virus immunity using a mouse model: from new insights to cancer immunotherapeutic applications
한국실험동물학회 학술발표대회 논문집
2022 .01
-
Th17 Cell and Inflammatory Infiltrate Interactions in Cutaneous Leishmaniasis: Unraveling Immunopathogenic Mechanisms
Immune Network
2024 .04
-
Influence of P53 on the radiotherapy response of hepatocellular carcinoma
Clinical and Molecular Hepatology
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0