지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Many patients with a traumatic brain injury (TBI) experience a range of sleep problems. Although some studies investigated the pathophysiology of sleep-wake cycle disturbances in TBI patients, it has not been clarified. This paper presents a middle aged female patient who showed sleep deprivation and sleep-wake cycle disturbances for approximately three months after TBI. The improvement in the subjective and objective sleep quality was shown by the sleep diary and actigraphy during this period. Moreover, the dim light melatonin onset (DLMO) had been delayed before returning to the normal range in 3 months. In addition, the patient showed an improvement in the neurocognitive function, including attention, memory and language function, along with a consolidation of the sleep-wake cycle. This case showed that the sleep disturbance following a TBI was probably caused by the disrupted melatonin rhythm based on the abnormality of the DLMO. In addition, the cognitive dysfunction after TBI could be associated with sleep-wake cycle disturbances because its gradual improvement occurred as the sleep disturbance diminished. Further studies on the change in circadian rhythm after a brain injury related to neurocognitive impairment are required.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Ouellet MC / 2015 / Sleep-wake disturbances after traumatic brain injury / Lancet Neurol 14:746~757
Duclos C / 2014 / Sleep and wake disturbances following traumatic brain injury / Pathol Biol(Paris) 62:252~261
Werner JK Jr / 2017 / TBI and sleep-wake disorders : pathophysiology, clinical management, and moving towards the future / Semin Neurol 37:419~432
Moore RY / 2002 / Suprachiasmatic nucleus organization / Cell Tissue Res 309:89~98
Lewy AJ / 2010 / Hormones, Brain and Behavior / Elsevier :2505~2528
Duclos C / 2014 / Sleep and wake disturbances following traumatic brain injury / Pathol Biol(Paris) 62:252~261
Werner JK Jr / 2017 / TBI and sleep-wake disorders : pathophysiology, clinical management, and moving towards the future / Semin Neurol 37:419~432
Moore RY / 2002 / Suprachiasmatic nucleus organization / Cell Tissue Res 309:89~98
Lewy AJ / 2010 / Hormones, Brain and Behavior / Elsevier :2505~2528
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