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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한자기공명의과학회 Investigative Magnetic Resonance Imaging Investigative Magnetic Resonance Imaging 제23권 제3호
- 발행연도
- 2019.1
- 수록면
- 241 - 250 (10page)
이용수
초록· 키워드
오류제보하기
Purpose: The purpose of this study was to determine the relation between quantitative magnetic resonance imaging biomarkers, and clinical performances in chronic phase of carbon monoxide intoxication. Materials and Methods: Eighteen magnetic resonance scans and cognitive evaluations were performed, on patients with carbon monoxide intoxication in chronic phase. Apparent diffusion coefficient (ADC) ratios of affected versus unaffected centrum semiovale, and corpus callosum were obtained. Signal intensity (SI) ratios between affected centrum semiovale, and normal pons in T2-FLAIR (fluidattenuated inversion recovery) images were obtained. The Mini-Mental State Exam, and clinical outcome scores were assessed. Correlation coefficients were calculated, between MRI and clinical markers. Patients were further classified into poor-outcome and good-outcome groups based on clinical performance, and imaging parameters were compared. T2-SI ratio of centrum semiovale was compared, with that of 18 sexmatched and age-matched controls. Results: T2-SI ratio of centrum semiovale was significantly higher in the pooroutcome group, than that in the good-outcome group and was strongly inversely correlated, with results from the Mini-Mental State Exam. ADC ratios of centrum semiovale were significantly lower in the poor outcome group than in the good outcome group, and were moderately correlated with the Mini-Mental State Exam score. Conclusion: A higher T2-SI and a lower ratio of ADC values in the centrum semiovale, may indicate presence of more severe white matter injury and clinical impairment. T2-SI ratio and ADC values in the centrum semiovale, are useful quantitative imaging biomarkers for correlation with clinical performance in individuals with carbon monoxide intoxication.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Hampson NB / 2007 / Carbon monoxide poisoning: a new incidence for an old disease / Undersea Hyperb Med 34:163~168
Weaver LK / 2009 / Clinical practice. Carbon monoxide poisoning / N Engl J Med 360:1217~1225
Ernst A / 1998 / Carbon monoxide poisoning / N Engl J Med 339:1603~1608
Beppu T / 2014 / The role of MR imaging in assessment of brain damage from carbon monoxide poisoning: a review of the literature / AJNR Am J Neuroradiol 35:625~631
Kim JH / 2003 / Delayed encephalopathy of acute carbon monoxide intoxication: diffusivity of cerebral white matter lesions / AJNR Am J Neuroradiol 24:1592~1597
Weaver LK / 2009 / Clinical practice. Carbon monoxide poisoning / N Engl J Med 360:1217~1225
Ernst A / 1998 / Carbon monoxide poisoning / N Engl J Med 339:1603~1608
Beppu T / 2014 / The role of MR imaging in assessment of brain damage from carbon monoxide poisoning: a review of the literature / AJNR Am J Neuroradiol 35:625~631
Kim JH / 2003 / Delayed encephalopathy of acute carbon monoxide intoxication: diffusivity of cerebral white matter lesions / AJNR Am J Neuroradiol 24:1592~1597
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