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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아소화기영양학회 Pediatric Gastroenterology, Hepatology & Nutrition Pediatric Gastroenterology, Hepatology & Nutrition 제22권 제5호
- 발행연도
- 2019.1
- 수록면
- 453 - 459 (7page)
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초록· 키워드
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Purpose: Jaundice accounts for most hospital admissions in the neonatal period. Nowadays, in addition to phototherapy, other auxiliary methods are used to reduce jaundice and the length of hospitalization. This study aimed to investigate the effect of probiotics on the treatment of hyper-bilirubinemia in full-term neonates. Methods: In this randomized clinical trial, 83 full-term neonates, who were admitted to the hospital to receive phototherapy in the first 6 months of 2015, were randomly divided into two groups: synbiotic (SG, n=40) and control (CG, n=43). Both groups received phototherapy but the SG also received 5 drops/day of synbiotics. Serum bilirubin, urine, stool, feeding frequency, and weight were measured daily until hospital discharge. A p-value<0.05 was considered statistically significant. Results: The mean total serum bilirubin in the SG was lower than that in the CG (9.38±2.37 and 11.17±2.60 mg/dL, respectively). The urine and stool frequency in the SG was significantly higher than that in the CG (p<0.05). The duration of hospitalization in the SG was shorter than that in the CG. Conclusion: Use of synbiotics as an adjuvant therapy had a significant treatment effect on jaundice in full-term neonates. Further studies including larger samples with long follow-up periods are essential to confirm the benefits of routine use of synbiotics in neonatal patients with jaundice.
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참고문헌 (26)
참고문헌 신청
Alex M / 2008 / Toward understanding the connections between infant jaundice and infant feeding / J Pediatr Nur 23:429~438
Martin RJ / 2006 / Fanaroff and Martin's neonatal perinatal medicine diseases of the fetus and infant / Mosby
Cohen SM / 2006 / Jaundice in the full-term newborn / Pediatr Nurs 32:202~208
American Academy of Pediatrics Subcommittee on Hyperbilirubinemia / 2004 / Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation / Pediatrics 114:297~316
Mahe E / 2009 / Neonatal blue-light phototherapy does not increase nevus count in 9-year-old children / Pediatrics 123:e896~900
Martin RJ / 2006 / Fanaroff and Martin's neonatal perinatal medicine diseases of the fetus and infant / Mosby
Cohen SM / 2006 / Jaundice in the full-term newborn / Pediatr Nurs 32:202~208
American Academy of Pediatrics Subcommittee on Hyperbilirubinemia / 2004 / Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation / Pediatrics 114:297~316
Mahe E / 2009 / Neonatal blue-light phototherapy does not increase nevus count in 9-year-old children / Pediatrics 123:e896~900
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