지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 212 - 223 (12page)
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초록· 키워드
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Recurrent pregnancy loss (RPL) is a common complication in obstetrics, affecting about 5% of women of childbearingage. An increase in the number of abortions results in escalation in the risk of miscarriage. Although concentratedresearch has identified numerous causes for RPL, about 50% of them remain unexplained. Pregnancy is a complexprocess, comprising fertilization, implantation, organ and tissue differentiation, and fetal growth, which is effectivelycontrolled by a number of both maternal and fetal factors. An example is the immune response, in which T cells andnatural killer cells participate, and inflammation mediated by tumor necrosis factor or colony-stimulating factor,which hinders embryo implantation. Furthermore, vitamin D affects glucose metabolism and inhibits embryonicdevelopment, whereas microRNA has a negative effect on the gene expression of embryo implantation anddevelopment. This review examines the causes of RPL from multiple perspectives, and focuses on the numerousfactors that may result in RPL.
목차
등록된 정보가 없습니다.
참고문헌 (102)
참고문헌 신청
Krieg S / 2015 / Immune function and recurrent pregnancy loss / Semin Reprod Med 33:305~312
Coulam CB / 1997 / Current clinical options for diagnosis and treatment of recurrent spontaneous abortion. Clinical guidelines recommendation committee for diagnosis and treatment of recurrent spontaneous abortion / Am J Reprod Immunol 38:57~74
Practice Committee of the American Society for Reproductive Medicine / 2012 / Evaluation and treatment of recurrent pregnancy loss: a committee opinion / Fertil Steril 98:1103~1111
Practice Committee of American Society for Reproductive Medicine / 2013 / Definitions of infertility and recurrent pregnancy loss : a committee opinion / Fertil Steril 99:63
Pan HT / 2018 / Proteomics and bioinformatics analysis of altered protein expression in the placental villous tissue from early recurrent miscarriage patients / Placenta 61:1~10
Coulam CB / 1997 / Current clinical options for diagnosis and treatment of recurrent spontaneous abortion. Clinical guidelines recommendation committee for diagnosis and treatment of recurrent spontaneous abortion / Am J Reprod Immunol 38:57~74
Practice Committee of the American Society for Reproductive Medicine / 2012 / Evaluation and treatment of recurrent pregnancy loss: a committee opinion / Fertil Steril 98:1103~1111
Practice Committee of American Society for Reproductive Medicine / 2013 / Definitions of infertility and recurrent pregnancy loss : a committee opinion / Fertil Steril 99:63
Pan HT / 2018 / Proteomics and bioinformatics analysis of altered protein expression in the placental villous tissue from early recurrent miscarriage patients / Placenta 61:1~10
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