지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
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Objectives: The resin infiltration technique is a promising alternative therapy for arresting the early dental caries. However, there are very few reports on the safety and biocompatibility of this technique. We evaluated various properties of resin infiltrant (RI) based on a triethylene glycol dimethacrylate (TEGDMA).The water sorption (Wsp) and water solubility (Wsl) was assessed. Additionally, the cytotoxicity of RI against both animal and human fibroblast cell lines was investigated. Methods: The RI of the Icon®, the first product developed for resin infiltration, is mainly composed of TEGDMA in the resin matrix. The Wsp and Wsl for the RI were measured in accordance with ISO 4049 specifications. Fourier-transform infrared spectroscopy (FTIR) was used for analyzing the polymerization before and after curing of RI. The cytotoxicity of RI against the mouse fibroblasts (L929) and human gingival fibroblasts (hTERT-hNOF) was evaluated using MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay and the data were analyzed using one-way analysis of variance. Results: Wsp and Wsl of the RI specimens were 53.37 μg/mm3 and 10.6 μg/mm3, respectively. FTIR analysis revealed a slightly higher degree of curing with longer irradiation time. The degree of conversion for RI was high (80.9%) after 40 seconds of light curing. There was a significant decrease in the viability of L929 and hTERThNOF cells at RI extraction solution concentrations above 50%, respectively, compared to that in the negative control ( p < 0.05). Conclusions: Even though the RI exhibited positive effect on the early prevention of dental caries, the clinicians should also consider the toxicity of RI on periodontal tissues.
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등록된 정보가 없습니다.
참고문헌 (31)
참고문헌 신청
Van P. Thompson / 2005 / Nonsurgical Treatment of Incipient and Hidden Caries / Dental Clinics of North America 49(4):905~921
Julian Fisher / 2012 / A new model for caries classification and management / The Journal of the American Dental Association 143(6):546~551
Sebastian PARIS / 2007 / Resin Infiltration of Artificial Enamel Caries Lesions with Experimental Light Curing Resins / Dental Materials Journal 26(4):582~588
Kielbassa AM / 2009 / Closing the gap between oral hygiene and minimally invasive dentistry: a review of the resin infiltration technique of incipient (proximal) enamel lesions / British Dental Journal 207(9):425~425
Paris S / 2009 / Masking of labial enamel white spot lesions by resin infiltration--a clinical report / Quintessence Int 40:713~718
Julian Fisher / 2012 / A new model for caries classification and management / The Journal of the American Dental Association 143(6):546~551
Sebastian PARIS / 2007 / Resin Infiltration of Artificial Enamel Caries Lesions with Experimental Light Curing Resins / Dental Materials Journal 26(4):582~588
Kielbassa AM / 2009 / Closing the gap between oral hygiene and minimally invasive dentistry: a review of the resin infiltration technique of incipient (proximal) enamel lesions / British Dental Journal 207(9):425~425
Paris S / 2009 / Masking of labial enamel white spot lesions by resin infiltration--a clinical report / Quintessence Int 40:713~718
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