Does Rapid Eye Movement Sleep Aggravate Obstructive Sleep Apnea?

김성희; 양찬주; 백종태; 현상민; 김천식; 이상암; 유명상

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자료유형: 학술저널

저자정보: 김성희 양찬주 백종태 현상민 김천식 이상암 유명상

저널정보: 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제12권 제2호

발행연도: 2019.1

수록면: 190 - 195 (6page)

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Objectives. To investigate the apnea-hypopnea index (AHI) according to the sleep stage in more detail after control of posture. Methods. Patients who underwent nocturnal polysomnography between December 2007 and July 2018 were retrospectively evaluated. Inclusion criteria were as follows: age >18 years, sleep efficacy >80%, and patients who underwent polysomnography only in the supine position (100% of the time). Patients were classified into different groups according to the methods: the first, rapid eye movement (REM)-dominant group (AHIREM/AHINREM >2), non-rapid eye movement (NREM)-dominant group (AHINREM/AHIREM >2), and non-dominant group; and the second, light sleep group (AHIN1N2>AHISWS) and slow wave sleep (SWS) group (AHISWS>AHIN1N2). Results. A total of 234 patients (mean age, 47.4±13.9 years) were included in the study. There were 108 patients (46.2%) in the REM-dominant group, 88 (37.6%) in the non-dominant group, and 38 (16.2%) in the NREM-dominant group. The AHI was significantly higher in the NREM-dominant group than in the REM-dominant group (32.9±22.9 events/hr vs. 18.3±9.5 events/hr, respectively). There were improvements in the AHI from stage 1 to SWS in NREM sleep with the highest level in REM sleep. A higher AHISWS than AHIN1N2 was found in 16 of 234 patients (6.8%); however, there were no significant predictors of these unexpected results except AHI. Conclusion. Our results demonstrated the highest AHI during REM sleep stage in total participants after control of posture. However, there were 16.2% of patients showed NREM-dominant pattern (AHINREM/AHIREM >2) and 6.8% of patients showed higher AHISWS than AHIN1N2. Therefore, each group might have a different pathophysiology of obstructive sleep apnea (OSA), and we need to consider this point when we treat the patients with OSA.

참고문헌 (23)

참고문헌 신청

Young T / 1993 / The occurrence of sleep-disordered breathing among middle-aged adults / N Engl J Med 328(17):1230~1235

Eckert DJ / 2008 / Pathophysiology of adult obstructive sleep apnea / Proc Am Thorac Soc 5(2):144~153

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