지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 347 - 356 (10page)
이용수
초록· 키워드
오류제보하기
ObjectiveTo assess the maternal demographic characteristics and uterine artery (UA) Doppler parameters at first and second trimesters of pregnancy as predictors for hypertensive disorders (HDs) and adverse perinatal outcomes.
MethodsThis prospective cohort study comprised 162 singleton low-risk women undergoing routine antenatal care. The left and right UA were assessed by color and pulsed Doppler and the mean pulsatility and resistance indices as well as the presence of a bilateral protodiastolic notch were recorded at 11 to 14 and 20 to 24 weeks’ gestation. Multilevel regression analysis was used to determine the effects of maternal characteristics and abnormal UA Doppler parameters on the incidence of HD, small for gestational age newborn, cesarean section rate, Apgar score <7 at 1st and 5th minute, and admission to the neonatal intensive care unit.
ResultsFifteen women (9.2%) developed HD. UA mean resistance index (RI), UA mean pulsatility index, and parity were independent predictors of HD. Compared to the pregnancies with a normal UA mean RI at the first and second trimesters, pregnancies with UA mean RI >95th percentile only at the first trimester showed an increased risk for HD (odds ratio, 23.25; 95% confidence interval, 3.47 to 155.73; P<0.01). Similar result was found for UA mean pulsatility index >95th percentile (odds ratio, 9.84; 95% confidence interval, 1.05 to 92.10; P=0.05). The model including maternal age, maternal and paternal ethnicity, occupation, parity and UA mean RI increased the relative risk for HD (area under receiver operating characteristics, 0.81).
ConclusionA first-trimester screening combining maternal characteristics and UA Doppler parameters is useful to predict HD in a low-risk population.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Redman CW / 2005 / Latest advances in understanding preeclampsia / Science 308:1592~1594
Ghulmiyyah L / 2012 / Maternal mortality from preeclampsia/eclampsia / Semin Perinatol 36:56~59
Espinoza J / 2006 / Normal and abnormal transformation of the spiral arteries during pregnancy / J Perinat Med 34:447~458
Toal M / 2007 / Usefulness of a placental profile in highrisk pregnancies / Am J Obstet Gynecol 196:363. e1~363. e7
Tuuli MG / 2011 / The role of serum markers and uterine artery Doppler in identifying at-risk pregnancies / Clin Perinatol 38:1~19
Ghulmiyyah L / 2012 / Maternal mortality from preeclampsia/eclampsia / Semin Perinatol 36:56~59
Espinoza J / 2006 / Normal and abnormal transformation of the spiral arteries during pregnancy / J Perinat Med 34:447~458
Toal M / 2007 / Usefulness of a placental profile in highrisk pregnancies / Am J Obstet Gynecol 196:363. e1~363. e7
Tuuli MG / 2011 / The role of serum markers and uterine artery Doppler in identifying at-risk pregnancies / Clin Perinatol 38:1~19
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