지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
티올특이성 산화환원 단백질인 peroxiredoxin (thiol-specific peroxiredoxin, Prx) 은 거의 모든 생명체에 존재하며, reactive oxgen species(ROS)을 제거하는 역할을 수행한다. 전자현미경/image processing을 이용하여 세포의방어기작에 중요한 기능을 수행하는 Prx의 구조를 분석하였다. Yeast-Prx는 크게 세 가지의 다른 형태 즉, 구 형태, ring 형태의 구조와 비 규칙적인 적은 입자로 구성되어 있음을 확인하였다. 또한 산화/환원 상태에서의 구조적 변화를 관찰하기위해 DTT와 H2O2를 처리 후 전자현미경을 관찰 하였다. 환원상태의(DTT 처리 후) yeast-Prx는 많은 decamer 구조를 보여주는 반면, 산화상태에서는(H2O2 처리 후) dimer나 구 형태의 구조를 보여 주고 있다. 또한 dimeric subunit간의 ionic interaction이 yeast-Prx의 oligomerization에 중요한 인자임을 확인하였다.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
/ 19791998 / Evidence that peroxiredoxins arenovel members of the thioredoxin fold superfamily : 133 2465 ~ 4 139 7 2468
/ 1991 / A novelATPase complex selectively accumulated upon heat shockis a major cellular component of thermophilic archaebacteria : 1711 ~ 1722
/ 19911991 / calculation of distortionmeasures from displacement maps 38 : 837 135 ~ 839 38 141
/ 1992 / Calciumactivatedpotassium transport and high molecular weightfrom of calpromotion : 21839 ~ 21843
/ 1993 / The structure of the surface layer of Methanoplanuslimicola obtained by a combined electron microscopyand scanning tunneling microscopy approach : 125 ~ 134
/ 1991 / A novelATPase complex selectively accumulated upon heat shockis a major cellular component of thermophilic archaebacteria : 1711 ~ 1722
/ 19911991 / calculation of distortionmeasures from displacement maps 38 : 837 135 ~ 839 38 141
/ 1992 / Calciumactivatedpotassium transport and high molecular weightfrom of calpromotion : 21839 ~ 21843
/ 1993 / The structure of the surface layer of Methanoplanuslimicola obtained by a combined electron microscopyand scanning tunneling microscopy approach : 125 ~ 134
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
참전복(Haliotis discus hannai)에서 분리한 peroxiredoxin 2 유전자의 분자생물학적 고찰 및 발현분석
생명과학회지
2014 .12
-
Peroxiredoxin System of Aspergillus nidulans Resists Inactivation by High Concentration of Hydrogen Peroxide-Mediated Oxidative Stress
Journal of Microbiology and Biotechnology
2018 .01
-
Molecular Analysis of Promoter and Intergenic Region Attenuator of the Vibrio vulnificus prx1ahpF Operon
Journal of Microbiology and Biotechnology
2015 .01
-
Peroxiredoxin II negatively regulates BMP2- induced osteoblast differentiation and bone formation via PP2A Cα-mediated Smad1/5/9 dephosphorylation
Experimental and Molecular Medicine
2019 .01
-
Identification and Characterization of a Novel Interaction between Two Distinct Peroxiredoxins, Prx2 and Bcp, of Vibrio vulnificus
한국미생물학회 학술대회논문집
2013 .05
-
The Cellular Roles of Vibrio vulnificus AhpC2, a Novel Bacterial Peroxiredoxin(Prx)
한국미생물학회 학술대회논문집
2011 .05
-
Synergistic effect of peroxiredoxin II antisense on cisplatininduced cell death
Experimental and Molecular Medicine
2002 .01
-
Working Mechanism of Peroxiredoxins (Prxs) and Sulphiredoxin1 (Srx1) in Arabidopsis thaliana
생명과학회지
2010 .12
-
Classification of Peroxiredoxin Subfamilies Using Regular Expressions
Genomics & informatics
2005 .01
-
An important role for peroxiredoxin II in survival of A549 lung cancer cells resistant to gefitinib
Experimental and Molecular Medicine
2015 .01
-
AhpR, a New OxyR-type Transcriptional Regulator of Vibrio vulnificus, Regulates Prx2 Expression in a Redox State-Dependent Manner
한국미생물학회 학술대회논문집
2013 .05
-
Construction and In vitro Study of a Prx 6/Luc Vector System for Screening Antioxidant Compounds in the Transgenic Mice
생명과학회지
2013 .02
-
CONCENTRATION DEPENDENCES OF GROUND-STATE AND EXCITED-STATE INTRAMOLECULAR PROTON TRANSFER OF PIROXICAM IN METHANOL
Journal of photoscience : an international journal officail organ of the korean society of photoscience
1994 .01
-
Mass Production of Yeast Spores from Compressed Yeast
Journal of Microbiology and Biotechnology
2005 .01
-
Proteomic Profiles of Mouse Neuro N2a Cells Infected with Variant Virulence of Rabies Viruses
Journal of Microbiology and Biotechnology
2011 .01
-
양식을 위한 먹이사료로서의 Yeast 균주의 개발 : 가능성 있는 효모 균주 ( Development of Yeast Strains as Feed for Aquaculture : Possible Yeast Strains )
생명과학회지
1996 .06
-
Diversity of Yeasts Associated with Natural Environments in Korea
The Journal of Microbiology
2002 .03
-
Occurrence of Yeasts in Cultivated Soils in El-Minia City, Egypt
Mycobiology
2002 .01
-
Stress Regulation Study of Ribosomal Proteins in Yeasts
한국미생물학회 학술대회논문집
2012 .05
-
Use of the Yeast 1.5-Hybrid System to Detect DNA-Protein-Protein Interactions
The Journal of Microbiology
2000 .06
이 논문의 저자 정보
최근 본 자료
댓글(0)
0