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Patient Attitudes and Considerations in Decision toward Participation in Clinical Trials of Chronic Diseases
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만성질환 임상시험 참여 대상자의 금전적 보상에 대한 태도와 참여결정 시 고려사항

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Type
Academic journal
Author
Journal
Korea College of Clinical Pharmacy 한국임상약학회지 한국임상약학회지 제27권 제1호 KCI Accredited Journals
Published
2017.1
Pages
30 - 37 (8page)

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Patient Attitudes and Considerations in Decision toward Participation in Clinical Trials of Chronic Diseases
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Research history (2)

2017

이주연 2017.01 Thesis
Patient Attitudes and Considerations in Decision toward Participation in Clinical Trials of Chronic Diseases
이주연 ,  Hongwon Jang ,  윤정현 and others 1 한국임상약학회지 2017.01 Academic journal
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Background: We investigated the impact of financial compensation on patients’ decision of participation in clinical trials and the related factors with patients’ attitudes and considerations. Methods: A survey questionnaire was placed from October 31 to November 16, 2017 to the subjects who were enrolled in the trials of chronic diseases. Patients’ socio-demographic characteristics were collected and the potential reasons for participating in the trials were assessed using 5-likert scores. Results: Sixty eight of 110 respondents (61.8%) indicated to participate clinical trials regardless of financial compensation. The differences were found between patients who were unwilling to participate without compensation and those who were willing to participate regardless of compensation in mean ages (43.9 years vs. 52.0 years, p<0.05), marital status (married, 47.6% vs 79.4%, p<0.01), religions (yes, 45.2% vs 67.6%, p<0.05) and monthly income (≥3 million won, 19.0% vs 45.6%, p<0.01). The potential reasons for participation in the trials between two groups were doctor’s suggestion (52.4% vs. 77.9%, p<0.01), the expectation of health improvement (54.8% vs.73.5%, p<0.05), the types and numbers of procedure (33.3% vs. 16.2%, p<0.05) and the duration of clinical trials (59.5% vs. 27.9%, p=0.001). In regression analysis, the monthly income of ≥ 3 million won (odd ratio, OR=3.221, p=0.026,) and the duration of trials (OR=0.290, p=0.017) were related to the group with the willingness to participate regardless of compensation. Conclusion: This stady showed that more than half of study subjects would participate in the clinical trials of chronic diseases regardless of financial compensation.
#Clinical trials #chronic disease #financial compensation

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References (22)

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/ / Korea Good Clinical Practice 2014 google schola / / Korea national enterprise for clinical trials google schola / / Ministry of employment and labor google schola / / The Korea association of chronic disease management google schola Barnes K / / Patients provide insight into trial participation google schola

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