메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류
인문학
인문학 일반 역사학 철학 종교학 어문학 기타 인문학
사회과학
사회과학 일반 경영학 관광학 교육학 군사학 문헌정보학 법학 사회학 신문방송학 심리과학 정치외교학 지리학 행정학 경제학 무역학 인류학 기타 사회과학
자연과학
자연과학 일반 물리학 생물학 생활과학 수학·통계학 천문학 지구과학 화학 기타 자연과학
공학
공학 일반 건축공학 기계공학 산업공학 재료·에너지공학 전기전자공학 조선해양공학 화학공학 컴퓨터학 기타공학
의약학
의학 일반 간호학 수의학 약학 한의학 기초의학 임상의학 기타 의약학
농수해양학
농수해양학 일반 농학 수산학 식품과학 임학 축산학 해상운송학 기타 농수해양학
예술체육학
예술 일반 디자인 미술 미용 사진 음악학 의상 체육 공연매체예술 기타 예술체육학
복합학
학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

ENG

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국환경보건학회 한국환경보건학회지 한국환경보건학회지 제42권 제1호
발행연도
2016.1
수록면
53 - 60 (8page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Objectives: Preservatives are commonly used in pharmaceuticals, cosmetics and other products to extend theexpiration date and prevent the growth of microorganisms. Preservatives are generally effective in controllingmold and inhibiting yeast growth, and against a wide range of bacterial attacks as well. They also adverselyaffect the quality of sperm and cause precocious puberty in children. This study was performed to analyze sevenpreservatives used in pharmaceuticals and personal care products. Methods: Five kinds of pharmaceuticals and personal care products (PPCPs) were examined for analysis witha high performance liquid chromatography-diode array detector. Each sample was homogenized and the targetedcompounds were extracted with methanol. The suspended particulate was removed by syringe filter. Next, thesample was injected into an HPLC system. The separation of the seven preservatives was achieved with a C18column and gradient mode. The accuracies were between 73% and 120% and precision was lower than 11.58%(RSD). Results: All of the calibration curves showed good linearity with a coefficient of determination (r2) over 0.999. Among the PPCP samples, the detection rate of preservatives was 32.5% for pharmaceuticals, 44.8% fortoothpaste, 76.9% for mouthwash, 40.0% for body lotion and 56.0% for wet tissues. The average concentrationsof the preservatives in PPCPs were BA 1141.0 mg/kg, MP 709.8 mg/kg, EP 624.9 mg/kg, PP 216.9 mg/kg, BP167.8 mg/kg, and TCS 538.2 mg/kg. The most frequently detected preservatives in pharmaceuticals and personalcare products were BA, MP and PP. The concentrations of preservatives exceeded Korean regulatory standardsin 11 samples of medicines, three of mouthwash and two of body lotion. Conclusion: We found that most of the PPCP samples contained various preservatives. It is necessary to identifywhich preservatives were used and to determine the level of preservatives in PPCPs and to assess the health riskto susceptible populations such as children.
#Cosmetics #pharmaceuticals #PPCPs #preservatives #toothpaste

목차

등록된 정보가 없습니다.

참고문헌 (20)

참고문헌 신청
Lee YM / 2008 / Optimization Plan of Use Standard for Preservatives :1~82 google schola Flores M / 1997 / Deterioration of raw materials and cosmetic products by preservative resistant microorganisms / International Biodeterioration & Biodegradation 40(2-4):157~160 google schola Soni MG / 2005 / Safety assessment of esters of p-hydroxybenzoic acid (parabens) / Food and Chemical Toxicology 43:985~1015 google schola Techakriengkrai I / 2007 / Analysis of benzoic acid and sorbic acid in Thai rice wines and distillates by solid-phase sorbent extraction and highperformance liquid chromatography / Journal of Food Composition and Analysis 20:220~225 google schola Judson R / 2009 / The Toxicity Data Landscape for Environmental Chemicals / Environmental Health Perspectives 117(5) google schola

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0