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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 940 - 948 (9page)
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초록· 키워드
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The aim of this study was to investigate the immune activity of Ailantias altissima as an active ingredient on the immune enhancement by mixing ethanol extract with lactic acid bacteria (LAB). The activity of NF-κB/AP1 transcription factor increased by NF-κB activity when mixed with LAB samples rather than with the extract alone. Nitric oxide (NO) production was similar in ethanol extract alone group and LPS treatment group. Mixing Ailantias altissima extract and lactic acid bacteria led to low NO production. The cytokine productivity of TNF-α significantly increased in Ailantias altissima extract when treated with LPS, and increased even more when mixed with lactic acid bacteria. The IL-1β cytokine production was high when the Ailantias altissima extract were treated alone, but no IL-1β cytokine was produced in the mixtures with isolates. The combination of the ethanol extract of the Ailantias altissima and the lactic acid bacteria was found to be effective in the immune function. Consequently, the ingredient to combine Ailantias altissima extract and lactic acid bacteria can be effectively used for development of the health functional food on the prevention and treatment of hypoimmunities. Key words: Ailantias altissima, immunity, lactic acid bacteria
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등록된 정보가 없습니다.
참고문헌 (34)
참고문헌 신청
Baeuerle PA / 1988 / I kappa B: A specific inhibitor of the NF-kappa B transcription factor / Science 242:540~546
Bosca L / 2005 / Nitric oxide and cell viability in inflammatory cells: A role for NO in macrophage function and fate / Toxicology 208:249~258
장보윤 / 2015 / 프로바이오틱스의 기능성 향상을 위한 배양법 / 한국식품위생안전성학회지 30(3):295~301
Gibson GR / 1995 / Dietary modulation of the human colonic microbiota: Introducing the concept of prebiotics / J Nutr 125:1401~1412
Higuchi M / 1990 / Cytolytic mechanisms of activated macrophages. Tumor necrosis factor and L-arginine-dependent mechanisms act synergistically as the major cytolytic mechanisms of activated macrophages / J Immunol 144:1425~1431
Bosca L / 2005 / Nitric oxide and cell viability in inflammatory cells: A role for NO in macrophage function and fate / Toxicology 208:249~258
장보윤 / 2015 / 프로바이오틱스의 기능성 향상을 위한 배양법 / 한국식품위생안전성학회지 30(3):295~301
Gibson GR / 1995 / Dietary modulation of the human colonic microbiota: Introducing the concept of prebiotics / J Nutr 125:1401~1412
Higuchi M / 1990 / Cytolytic mechanisms of activated macrophages. Tumor necrosis factor and L-arginine-dependent mechanisms act synergistically as the major cytolytic mechanisms of activated macrophages / J Immunol 144:1425~1431
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