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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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A micromachined fluidic structure for the introduction of liquid samples into a chip-based sensor array composed of individually addressable polymeric microbeads has been developed. The structure consists of a separately attached cover glass, a single silicon chip having micromachined channels and microbead storage cavities, and a glass carrier. In our sensor array, transduction occurs via colorimetric and fluorescence changes to receptors and indicator molecules that are covalently attached to termination sites on the polymeric microbeads. Data streams are acquired for each of the individual microbeads using a CCD. One of the key parts of the structure is a passive fluid introduction system driven only by capillary force. The velocity of penetration of a horizontal capillary for the device having a rectangular cross section has been derived, and it is quite similar to the Washburn Equation calculated for a pipe with a circular cross section having uniform radius. The test results show that this system is useful in a μ-TAS and biomedical applications.
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참고문헌 (10)
참고문헌 신청
C.-J. Kim / 2000 / Microfluidic Using the Surface Tension Force in Microscale 4177 : 49 ~ 54
E. D. Washburn / 1921. / The Dynamics of Capillary Flow 17 : 273 ~
F. W. Went / 1968. / The Size of Man 56 : 400 ~ 413
G. Kovacs / 1998. / Micromachined Transducers Sourcebook
Goodey, A / 2001. / Development of Multianalyte Sensor ArraysComposed of Chemical Derivatized Polymeric Microspheres Localized in Micromachined Cavities 123 : 2559 ~ 2570
E. D. Washburn / 1921. / The Dynamics of Capillary Flow 17 : 273 ~
F. W. Went / 1968. / The Size of Man 56 : 400 ~ 413
G. Kovacs / 1998. / Micromachined Transducers Sourcebook
Goodey, A / 2001. / Development of Multianalyte Sensor ArraysComposed of Chemical Derivatized Polymeric Microspheres Localized in Micromachined Cavities 123 : 2559 ~ 2570
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