지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 702 - 708 (7page)
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초록· 키워드
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Background: Behçet’s disease (BD) is a chronic, recurrent inflammatory systemic vasculitis. Evidence for increased atherosclerosis in BD has been observed. The relation between cardiovascular risk factors and increased atherosclerosis in patients with BD is still controversial. Objective: We performed this study to evaluate arterial stiffness in patients with BD by using noninvasive radiological methods such as carotid artery intima-media thickness (CIMT), ankle-brachial pressure index (ABPI), coronary artery calcium score (CACaS), and their relation to serum fetuin-A levels, which was recently found to be important in vascular calcification.
Methods: This prospective study included 26 patients with BD and 25 control subjects. In all patients, the CIMT, ABPI, CACaS, and serum fetuin-A levels were examined. Results: The CIMT and CACaS were statistically higher and the ABPI was statistically lower in BD patients than in the control group. All p-values were ＜0.001. Positive correlations were found between the CACaS and CIMT, and negative correlations were found between the CACaS and ABPI. Although the values of fetuin-A were higher in BD, the difference was not statistically significant (p=0.064). However, the correlations found between fetuin-A levels and CIMT and between fetuin-A levels and CACaS were significant. Conclusion: The CIMT, CACaS, and ABPI are all useful in detecting structural and functional vascular damage in BD.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Aboyans V / 2012 / Measurement and interpretation of the anklebrachial index: a scientific statement from the American Heart Association / Circulation 126 : 2890 ~ 2909
Agatston AS / 1990 / Quantification of coronary artery calcium using ultrafast computed tomography / J Am Coll Cardiol 15 : 827 ~ 832
Alpsoy E / 2007 / Clinical features and natural course of Behcet's disease in 661 cases: a multicentre study / Br J Dermatol 157 : 901 ~ 906
Bechet H / 1937 / On relapsing, aphthous ulcers of the mouth, eye and genitelia caused by a virus / Dermatol Wochenschr 105 : 1152 ~ 1157
Bots ML / 1996 / Common carotid intima-media thickness as an indicator of atherosclerosis at other sites of the carotid artery. The Rotterdam Study / Ann Epidemiol 6 : 147 ~
Agatston AS / 1990 / Quantification of coronary artery calcium using ultrafast computed tomography / J Am Coll Cardiol 15 : 827 ~ 832
Alpsoy E / 2007 / Clinical features and natural course of Behcet's disease in 661 cases: a multicentre study / Br J Dermatol 157 : 901 ~ 906
Bechet H / 1937 / On relapsing, aphthous ulcers of the mouth, eye and genitelia caused by a virus / Dermatol Wochenschr 105 : 1152 ~ 1157
Bots ML / 1996 / Common carotid intima-media thickness as an indicator of atherosclerosis at other sites of the carotid artery. The Rotterdam Study / Ann Epidemiol 6 : 147 ~
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