지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 439 - 443 (5page)
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초록· 키워드
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Erdheim-Chester disease (ECD) is a rare, non-Langerhans cell histiocytosis of unknown etiology, characterized by multiorgan involvement. ECD is usually diagnosed on the basis of characteristic radiologic and histopathological findings.
Lesions may be skeletal and/or extraskeletal in location, and may include the skin, lung, heart, and central nervous system. We describe here a 68-year-old man with multiple yellowish plaques and a pinkish nodule on his face and scalp. He had been previously diagnosed with diabetes insipidus, and recently complained of coughing and dyspnea.
Imaging studies showed multiple osteosclerotic lesions of the bones, a moderate amount of pericardial effusion, and multifocal infiltrative lesions in the perirenal space. Histopathological examination of the skin lesions revealed dermal infiltration of foamy histiocytes with multinuclear giant cells. Moreover, laparoscopic biopsy of the perirenal tissue revealed fibrosis with infiltrating foamy histiocytes being CD68-positive and S100-negative. Based on these findings, he was diagnosed with ECD with extraskeletal manifestations, and treated with interferonalpha.
(Ann Dermatol 22(4) 439∼443, 2010)
목차
등록된 정보가 없습니다.
참고문헌 (9)
참고문헌 신청
Breuil V / 2002 / Erdheim-Chester disease:typical radiological bone features for a rare xanthogranulomatosis / Ann Rheum Dis 61 : 199 ~ 200
Dickson BC / 2008 / Systemic Erdheim-Chester disease / Virchows Arch 452 : 221 ~ 227
Greenberger JS / 1981 / Results of treatment of 127 patients with systemic histiocytosis / Medicine(Baltimore) 60 : 311 ~ 338
Haroche J / 2006 / Variability in the efficacy of interferon-alpha in Erdheim-Chester disease by patient and site of involvement:results in eight patients / Arthritis Rheum 5
Myra C / 2004 / Treatment of Erdheim-Chester disease with cladri bine:a rational approach / Br J Ophthalmol 88 : 844 ~ 847
Dickson BC / 2008 / Systemic Erdheim-Chester disease / Virchows Arch 452 : 221 ~ 227
Greenberger JS / 1981 / Results of treatment of 127 patients with systemic histiocytosis / Medicine(Baltimore) 60 : 311 ~ 338
Haroche J / 2006 / Variability in the efficacy of interferon-alpha in Erdheim-Chester disease by patient and site of involvement:results in eight patients / Arthritis Rheum 5
Myra C / 2004 / Treatment of Erdheim-Chester disease with cladri bine:a rational approach / Br J Ophthalmol 88 : 844 ~ 847
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