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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 164 - 172 (9page)
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Background: In adult patients with chronic urticaria (CU), the prevalence of food allergy is low compared to childhood patients. However, there are many patients who report food-related aggravation of CU, and some of them may have histamine intolerance. Objective: The aim of this study was to evaluate the role of ingested histamine and to investigate the effect of a histamine-free diet in adult patients with CU. Methods: Twenty-two adult patients with CU were enrolled. Foods with high amounts of histamine were prohibited to all patients for four weeks. The degree of severity of the urticaria was evaluated using the urticaria severity score (USS) and urticaria activity score (UAS). Plasma histamine levels and diamine oxidase (DAO) activity were determined and compared before (baseline) and after the histamine-free diet. Results: Twenty-two adult patients were recruited and completed four weeks of histamine-free diet. The USS and UAS scores each showed significant differences before and after the histamine-free diet (p=0.010, p=0.006). There was a significant reduction in plasma histamine level after the histamine free-diet, compared with baseline (p=0.010). However, DAO activity did not change after the histamine-free diet (p=0.165). Conclusion: Our study suggested that ingested histamine might be related to CU severity and that a histamine- free diet is helpful for treatment of adult patients with CU.
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참고문헌 (32)
참고문헌 신청
Kaplan AP / 2009 / Urticaria and angioedema;Middleton's allergy: principles and practice. 7th ed. / Mosby Elsevier :1063
Greaves M / 2000 / Chronic urticaria / J Allergy Clin Immunol 105:664~672
Champion RH / 1988 / Urticaria: then and now / Br J Dermatol 119:427~436
Khan DA / 2008 / Chronic urticaria: diagnosis and management / Allergy Asthma Proc 29:439~446
Wantke F / 1993 / Histamine-free diet: treatment of choice for histamine-induced food intolerance and supporting treatment for chronic headaches / Clin Exp Allergy 23:982~985
Greaves M / 2000 / Chronic urticaria / J Allergy Clin Immunol 105:664~672
Champion RH / 1988 / Urticaria: then and now / Br J Dermatol 119:427~436
Khan DA / 2008 / Chronic urticaria: diagnosis and management / Allergy Asthma Proc 29:439~446
Wantke F / 1993 / Histamine-free diet: treatment of choice for histamine-induced food intolerance and supporting treatment for chronic headaches / Clin Exp Allergy 23:982~985
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