지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 232 - 236 (5page)
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초록· 키워드
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Melkersson–Rosenthal syndrome (MRS) is an uncommon granulomatous disease characterized by the triad of relapsing facial paralysis, orofacial swelling, and fissured tongue.
Genital swelling in MRS is rarely reported. We presented the first case of complete MRS with genital swelling in a child.
Biopsy examinations of both the child’s lower lip and penis showed noncaseating granuloma and intralymphatic granuloma infiltration. No symptoms or signs of other systemic disease (Crohn’s disease or sarcoidosis) were observed after 2 years of follow-up. Genetic screening for CARD15/NOD2 in this patient showed negative, which further confirmed the diagnosis of MRS. Eleven other cases of suspected complete or incomplete MRS with genitalia involved were reviewed.
Our case emphasizes the specific clinical feature of MRS with genitalia involved, which was genetically different from Crohn’s disease and could be an independent entity.
Lymphatic obstruction is responsible for localized edema in MRS.
목차
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참고문헌 (19)
참고문헌 신청
Elias MK. / 2013 / The Melkersson-Rosenthal syndrome : a retrospective study of biopsied cases / J Neurol 260:138~143
Ziem PE. / 2000 / Melkersson-Rosenthal syndrome in childhood : a challenge in differential diagnosis and treatment / Br J Dermatol 143:860~863
Liu R. / 2013 / Melkersson-Rosenthal syndrome : a review of seven patients / J Clin Neurosci 20:993~995
Dodi I. / 2006 / A monosymptomatic Melkersson-Rosenthal syndrome in an 8-year old boy / Acta Biomed 77:20~23
Knopf B. / 1992 / Monosymptomatic Melkersson-Rosenthal syndrome with subsequent vulvitis and perivulvitis granulomatosa / Hautarzt 43:711~713
Ziem PE. / 2000 / Melkersson-Rosenthal syndrome in childhood : a challenge in differential diagnosis and treatment / Br J Dermatol 143:860~863
Liu R. / 2013 / Melkersson-Rosenthal syndrome : a review of seven patients / J Clin Neurosci 20:993~995
Dodi I. / 2006 / A monosymptomatic Melkersson-Rosenthal syndrome in an 8-year old boy / Acta Biomed 77:20~23
Knopf B. / 1992 / Monosymptomatic Melkersson-Rosenthal syndrome with subsequent vulvitis and perivulvitis granulomatosa / Hautarzt 43:711~713
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