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자료유형
학술저널
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저널정보
대한피부과학회 Annals of Dermatology Annals of Dermatology 제21권 제3호
발행연도
2009.1
수록면
230 - 236 (7page)

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Background: UVA1 phototherapy has recently demonstrated high levels of efficacy and tolerability for treating a variety of inflammatory and neoplastic skin diseases. Objective: The purpose of the present study was to assess the clinical efficacy of UVA1 (340∼400 nm) phototherapy for treating pityriasis rosea and to assess the course of the disease after treatment. Methods: Fifteen patients with extensive pityriasis rosea were treated with low-dose UVA1 phototherapy (starting at 10∼20 J/cm2 and then it was increased to 30 J/cm2). The treatments were given 2∼3 times a week until complete clearance of lesions was achieved or until there was partial improvement without further amelioration, in spite of 5 additional treatments. The rate of clearing was monitored by estimating the pityriasis rosea severity (PRSS) score and the pruritus score. Results: The extent of disease (PRSS) in all 15 patients lessened during the study (30.1±3.6 vs. 2.0±1.6, respectively, p<0.05). The overall reduction of the PRSS showed a significant improvement after the second or third treatment. The pruritus of 12 of 15 patients lessened during the treatment period, and it was unchanged in the remaining 3 patients. The mean previous duration of disease was 11.2±4.9 days and this did not interfere with the successful outcome of UVA1 phototherapy. Conclusion: This study shows that UVA1 phototherapy is a useful, well-tolerated treatment option for patients suffering from pityriasis rosea with extensive eruptions and considerable pruritus.

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