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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 592 - 596 (5page)
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Elephantiasis is a symptom characterized by the thickening of the skin and underlying tissues in the legs. Pretibial myxedema (PTM) is a non-frequent manifestation of autoimmune thyroiditis, particularly Graves’ disease. Lesions of myxedema occur most commonly on the pretibial surfaces, also develop at sites of previous injury or scars and other areas. A 49-year-old male presented with severe elephantiasis on the both pretibial areas, dorsum of the feet, ankles and toes. Twenty years previously, he had received radioactive iodine treatment for thyrotoxicosis. Laboratory tests showed that the patient’s thyroid function was normal, but the level of thyroid stimulating hormone (TSH) receptor antibodies was very high (＞40 IU/L). The biopsy confirmed PTM. Interestingly, the connective tissue was stained with the TSH receptor antibodies in the deep dermis. Elephantiasic PTM is a severe form of the myxedema and there is few reported case. We report a rare case of PTM with appearance of severe elephantiasis.
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등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Yimer M / 2015 / Epidemiology of elephantiasis with special emphasis on podoconiosis in Ethiopia: a literature review / J Vector Borne Dis 52:111~115
Davies TF / 2000 / Trauma and pressure explain the clinical presentation of the Graves' disease triad / Thyroid 10:629~630
Fatourechi V / 2005 / Pretibial myxedema: pathophysiology and treatment options / Am J Clin Dermatol 6:295~309
Schwartz KM / 2002 / Dermopathy of graves' disease (pretibial myxedema): long-term outcome / J Clin Endocrinol Metab 87:438~446
Rapoport B / 2000 / Elephantiasic pretibial myxedema: insight into and a hypothesis regarding the pathogenesis of the extrathyroidal manifestations of Graves' disease / Thyroid 10:685~692
Davies TF / 2000 / Trauma and pressure explain the clinical presentation of the Graves' disease triad / Thyroid 10:629~630
Fatourechi V / 2005 / Pretibial myxedema: pathophysiology and treatment options / Am J Clin Dermatol 6:295~309
Schwartz KM / 2002 / Dermopathy of graves' disease (pretibial myxedema): long-term outcome / J Clin Endocrinol Metab 87:438~446
Rapoport B / 2000 / Elephantiasic pretibial myxedema: insight into and a hypothesis regarding the pathogenesis of the extrathyroidal manifestations of Graves' disease / Thyroid 10:685~692
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