지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 368 - 374 (7page)
이용수
초록· 키워드
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Background/Aims: The aims of the study were to identify whether a mucous-cap predicts the presence of serrated polyps, and todetermine whether additional endoscopic findings predict the presence of a sessile serrated adenomas/polyp (SSA/P). Methods: We analyzed 147 mucous-capped polyps with corresponding histology, during 2011–2014. Eight endoscopic features (presenceof borders, elevation, rim of debris, location in the colon, size ≥10 mm, varicose vessels, nodularity, and alteration in mucosal folds) ofmucous-capped polyps were examined to see if they can predict SSA/Ps. Results: A total of 86% (n=126) of mucous-capped polyps were from the right sided serrated pathway (right-sided hyperplastic [n=83],SSA/Ps [n=43], traditional serrated adenoma [n=1]), 10% (n=15) were left-sided hyperplastic polyps, and 3% (n=5) were from theadenoma-carcinoma sequence. The presence of a mucous cap combined with varicose vessels was the only significant predictor forSSA/Ps. The other seven characteristics were not found to be statistically significant for SSA/Ps, although location in the colon and thepresence of nodularity trended towards significance. Conclusions: Our study suggests that mucous-capped polyps have high predictability for being a part of the serrated pathway. Gastroenterologists should be alert for a mucous-capped polyp with varicose veins, as these lesions have a higher risk of SSA/P.
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등록된 정보가 없습니다.
참고문헌 (33)
참고문헌 신청
Vogelstein B / 1988 / Genetic alterations during colorectal-tumor development / N Engl J Med 319:525~532
Sillars-Hardebol AH / 2012 / The adenoma hunt in colorectal cancer screening: defining the target / J Pathol 226:1~6
East JE / 2008 / Sporadic and syndromic hyperplastic polyps and serrated adenomas of the colon: classification, molecular genetics, natural history, and clinical management / Gastroenterol Clin North Am 37:25~46
Arnold CA / 2011 / The serrated pathway of neoplasia: new insights into an evolving concept / Diagn Histopathol (Oxf) 17:367~375
Leggett B / 2010 / Role of the serrated pathway in colorectal cancer pathogenesis / Gastroenterology 138:2088~2100
Sillars-Hardebol AH / 2012 / The adenoma hunt in colorectal cancer screening: defining the target / J Pathol 226:1~6
East JE / 2008 / Sporadic and syndromic hyperplastic polyps and serrated adenomas of the colon: classification, molecular genetics, natural history, and clinical management / Gastroenterol Clin North Am 37:25~46
Arnold CA / 2011 / The serrated pathway of neoplasia: new insights into an evolving concept / Diagn Histopathol (Oxf) 17:367~375
Leggett B / 2010 / Role of the serrated pathway in colorectal cancer pathogenesis / Gastroenterology 138:2088~2100
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