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ObjectiveTo investigate the correlation between bladder wall thickness (BWT) measured by ultrasonography and lower urinarytract dysfunction (LUTD) in patients with lower urinary tract symptoms (LUTS). MethodsForty-eight women with LUTS who underwent urodynamic study and BWT by ultrasonography as outpatients werestudied. We assessed LUTS during a medical examination by interview. The thinnest part of the bladder wall wasmeasured by a transabdominal ultrasonography. We excluded patients who had visited another hospital previouslybecause we did not know what treatment they had received, including medications, behavioral therapy, or othertreatments. We constructed receiver operating characteristic (ROC) curves for diagnosis of LUTD and also determinedreliable BWT criteria by calculating the area under the curve. Statistical analyses were performed using theKolmogorov-Smirnov method and Student's t-test. ResultsThe mean age, body mass index, and duration of symptoms were 59.9±9.7 years, 26.06±3.4 kg/m2, and 53.4±38.2months, respectively. Urodynamic study parameters (Valsalva leak point pressure, maximal urethral closure pressure,functional length, and postvoid residual volume) were lower in patients with BWT <3 mm; however, these differenceswere not significant. Patients with BWT ≥3 mm developed a hypoactive bladder (P=0.009) and intrinsic sphincterdeficiency (ISD) (P=0.001) at a significantly higher rate. According to the ROC analysis, the best BWT cut-off value was3 mm for overactive bladder diagnosis. ConclusionWomen with LUTD showed higher BWT values (≥3 mm), especially patients with hypoactive bladder and ISD. Sonographic evaluation of BWT is an easy, fast, and noninvasive method for possible diagnostic tool for LUTD.

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