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자료유형
학술저널
저자정보
저널정보
대한산부인과학회 Obstetrics & Gynecology Science Obstetrics & Gynecology Science 제61권 제3호
발행연도
2018.1
수록면
319 - 327 (9page)

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ObjectivePlacental site trophoblastic tumor (PSTT) is the rarest form of gestational trophoblastic disease (GTD) and theoptimum management is still controversial. In this study, we analyzed the clinical features, treatment, and outcomesof 6 consecutive patients with PSTT treated in our institution. MethodsThe electronic medical record database of Samsung Medical Center was screened to identify patients with PSTT from1994 to 2017. Medical records for the details of each patient's clinical features and treatment were extracted andreviewed. This study was approved Institutional Review Board of our hospital. ResultsA total of 418 cases of GTD, 6 (1.4%) patients with PSTT were identified. The median age of the patients was 31years. The antecedent pregnancy was term in all 5 cases with available antecedent pregnancy information and themedian interval from pregnancy to diagnosis of PSTT was 8 months. The median titer of serum beta human chorionicgonadotropin (β-hCG) at diagnosis was 190.9 mIU/mL. Five (83.3%) patients presented with irregular vaginal bleedingand one (16.7%) had amenorrhea. All patients had disease confined to the uterus without metastasis at diagnosis andwere successfully treated by hysterectomy alone. All of them were alive without disease during the follow-up period. ConclusionIn this study, we observed low level serum β-hCG titer and irregular vaginal bleeding with varying interval afterantecedent term pregnancy were most common presenting features of PSTT. In addition, we demonstratedhysterectomy alone was successful for the treatment of stage I disease of PSTT.

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