지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 565 - 570 (6page)
이용수
초록· 키워드
오류제보하기
Objective: This study aims to investigate whether there are any notable etiologies for repeated biochemical pregnancy (RBP) and, if so, to compare those etiologies associated with repeated spontaneous abortion in infertile couples who have undergone in vitro fertilization (IVF).
Methods: Forty-four infertile couples who underwent IVF and experienced RBP were included in this study. RBP was defined as more than 2 early pregnancy losses that occurred before the detection of a gestational sac, with ectopic pregnancies specifically excluded by serial serum beta human chorionic gonadotropin evaluation. Forty-three infertile couples who underwent IVF and experienced recurrent spontaneous abortion (RSA) were included as a control group. Karyotype analysis, anatomic evaluation of uterus, endocrine and immunological evaluation were performed. In addition, the number of pregnant women confirmed by 12 weeks' gestation was compared between groups.
Results: Immunological factors (RSA: 20.9% vs. RBP: 29.5%, P=0.361), diminished ovarian reserve (RSA: 10.9% vs. RBP: 17%, P=0.552), and parental chromosomal abnormalities (RSA: 18.6% vs. RBP: 9.1%, P=0.218) were not different between groups. Additionally, the incidence of uterine factors (RSA: 11.6% vs. RBP: 4.6%, P=0.206), unknown cause (RSA: 48.8% vs. RBP: 54.5%, P=0.161), and the pregnancy outcome identified until 12 weeks' gestation (RSA: 46.5% vs. RBP: 38.6%, P=0.520) did not differ between groups.
Conclusion: In the present study, the causes of RBP after IVF were similar to those of RSA. Accordingly, we suggest that efforts should be made to define the etiology of RBP, particularly for infertile couples, and that possible management strategies should be offered.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Annan JJ / 2013 / Biochemical pregnancy during assisted conception: a little bit pregnant / J Clin Med Res 5 : 269 ~ 274
Bulmer JN / 1991 / Granulated lymphocytes in human endometrium:histochemical and immunohistochemical studies / Hum Reprod 6 : 791 ~ 798
Bussen S / 1995 / Thyroid autoantibodies in euthyroid non-pregnant women with recurrent spontaneous abortions / Hum Reprod 10 : 2938 ~ 2940
Committee on Practice Bulletins?Gynecology / 2015 / The American College of Obstetricians and Gynecologists Practice Bulletin no. 150. Early pregnancy loss / Obstet Gynecol 1
Coulam CB / 1995 / Systemic CD56+ cells can predict pregnancy outcome / Am J Reprod Immunol 33 : 40 ~ 46
Bulmer JN / 1991 / Granulated lymphocytes in human endometrium:histochemical and immunohistochemical studies / Hum Reprod 6 : 791 ~ 798
Bussen S / 1995 / Thyroid autoantibodies in euthyroid non-pregnant women with recurrent spontaneous abortions / Hum Reprod 10 : 2938 ~ 2940
Committee on Practice Bulletins?Gynecology / 2015 / The American College of Obstetricians and Gynecologists Practice Bulletin no. 150. Early pregnancy loss / Obstet Gynecol 1
Coulam CB / 1995 / Systemic CD56+ cells can predict pregnancy outcome / Am J Reprod Immunol 33 : 40 ~ 46
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