지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제26권 제3호
- 발행연도
- 2016.1
- 수록면
- 441 - 451 (11page)
이용수
초록· 키워드
오류제보하기
Squalene is a linear triterpene formed via the MVA or MEP biosynthetic pathway and is widely distributed in bacteria, fungi, algae, plants, and animals. Metabolically, squalene is used not only as a precursor in the synthesis of complex secondary metabolites such as sterols, hormones, and vitamins, but also as a carbon source in aerobic and anaerobic fermentation in microorganisms. Owing to the increasing roles of squalene as an antioxidant, anticancer, and anti-inflammatory agent, the demand for this chemical is highly urgent. As a result, with the exception of traditional methods of the isolation of squalene from animals (shark liver oil) and plants, biotechnological methods using microorganisms as producers have afforded increased yield and productivity, but a reduction in progress. In this paper, we first review the biosynthetic routes of squalene and its typical derivatives, particularly the squalene synthase route. Second, typical biotechnological methods for the enhanced production of squalene using microbial cell factories are summarized and classified. Finally, the outline and discussion of the novel trend in the production of squalene with several updated events to 2015 are presented.
목차
등록된 정보가 없습니다.
참고문헌 (77)
참고문헌 신청
Auffray B / 2007 / Protection against singlet oxygen, the main actor of sebum squalene peroxidation during sun exposure, using Commiphora myrrha essential oil / Int. J. Cosmet. Sci 29:23~29
Berger A / 2003 / Cholesterol-lowering properties of Amaranth grain and oil in hamsters / Int. J. Vitam. Nutr. Res 73:39~47
Bhargava P / 2010 / Cloning, overexpression and characterization of Leishmania donovani squalene synthase / FEMS Microbiol. Lett 311:82~92
Bhat WW / 2012 / Molecular cloning, bacterial expression and promoter analysis of squalene synthase from Withania somnifera (L.) Dunal / Gene 499:25~36
Bhattacharjee P / 2001 / Studies on fermentative production of squalene / World J. Microbiol. Biotechnol 17:811~816
Berger A / 2003 / Cholesterol-lowering properties of Amaranth grain and oil in hamsters / Int. J. Vitam. Nutr. Res 73:39~47
Bhargava P / 2010 / Cloning, overexpression and characterization of Leishmania donovani squalene synthase / FEMS Microbiol. Lett 311:82~92
Bhat WW / 2012 / Molecular cloning, bacterial expression and promoter analysis of squalene synthase from Withania somnifera (L.) Dunal / Gene 499:25~36
Bhattacharjee P / 2001 / Studies on fermentative production of squalene / World J. Microbiol. Biotechnol 17:811~816
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Development analysis of squalene produced from cyanobacteria
한국분석과학회 학술대회
2016 .11
-
Evaluation of Photosynthetic Squalene Production of Engineered Cyanobacteria Using the Chemical Inducer-Free Expression System
한국미생물·생명공학회지
2021 .09
-
Preliminary study for aging of latent fingerprints on nonporous substrate
분석과학
2023 .04
-
Microbial Cell Factory for Isoprenoids Production
한국미생물학회 학술대회논문집
2016 .04
-
Isolation and Identification of Ground Microorganism to Find New Beneficial Microbial Agents
한국미생물학회 학술대회논문집
2016 .04
-
About the Importance of Membrane Transport for Microbial Chemical Production
한국미생물학회 학술대회논문집
2021 .08
-
Convergence of Distinct Secondary Metabolite Biosynthetic Gene Clusters Driving Chemical Innovation in Fungi
한국미생물학회 학술대회논문집
2022 .10
-
Microbial Diversity, Biotechnological Potential and Adaptation to Deep Sea Hydrothermal Vents Conditions
한국미생물학회 학술대회논문집
2016 .04
-
Optimization of a Fermentation Process to Improve Microbial Production of Heme
한국미생물학회 학술대회논문집
2022 .10
-
Isolation and Identification of Secondary Metabolites from the Ovary of Nelumbo nucifera
생명과학회지
2016 .10
-
The study of fingerprint degradation and composition according to aging(Ⅱ)
한국분석과학회 학술대회
2021 .11
-
Microbial Phenol Production in Metabolically Engineered Escherichia coli
한국미생물학회 학술대회논문집
2015 .04
-
Novel Metabolic Pathway for Microbial Production of Four-, Five-, and Six-carbon Lactams
한국미생물학회 학술대회논문집
2019 .04
-
The Pragmatic Introduction and Expression of Microbial Transgenes in Plants
Journal of Microbiology and Biotechnology
2018 .01
-
Microbial Production of Lactate-Containing Polymers in Metabolically Engineered Escherichia coli
한국미생물학회 학술대회논문집
2015 .04
-
Microbial Niches in Raw Ingredients Determine Microbial Community Assembly during Kimchi Fermentation
한국미생물학회 학술대회논문집
2020 .10
-
Draft Genome Analysis of Antimicrobial Streptomyces Isolated from Himalayan Lichen
Journal of Microbiology and Biotechnology
2019 .01
-
Recent Trends of Oxygen Reduction Catalysts in Microbial Fuel Cells
한국미생물학회 학술대회논문집
2022 .10
-
Microbial Metabolite in Metabolic Diseases and Drug Responses
한국미생물학회 학술대회논문집
2021 .08
-
Advances in the Structures, Pharmacological Activities, and Biosynthesis of Plant Diterpenoids
Journal of Microbiology and Biotechnology
2024 .08
이 논문의 저자 정보
최근 본 자료
댓글(0)
0