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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제18권 제12호
- 발행연도
- 2008.1
- 수록면
- 1,884 - 1,889 (6page)
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초록· 키워드
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The β-lactamase inhibitory protein, BLIP-II, found in the
culture supernatant of Streptomyces exfoliatus SMF19, shows
no discernible sequence identity with other β-lactamase
inhibitory proteins identified in Streptomyces spp. A null
mutant of the gene encoding BLIP-II (bliB::hygr) showed
a bald appearance on solid media. Although BLIP-II was
initially isolated from the supernatant of submerged cultures,
sites of BLIP-II accumulation were seen in the cell envelope.
Mutation of bliB was also associated with changes in the
formation of septa and condensation of the chromosomal
DNA associated with sporulation. The bliB mutant
exhibited infrequent septa, showing dispersed chromosomal
DNA throughout the mycelium, whereas the condensed
chromosomes of the wild-type were separated by regularly
spaced septa giving the appearance of a string of beads.
Therefore, on the basis of these results, it is suggested that
BLIP-II is a regulator of morphological differentiation in
S. exfoliatus SMF19.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Blazquez, J. / 1993 / Characterization of a new TEM-type β-lactamase resistant to clavulanate, sulbactam, and tazobactam in a clinical isolate of Escherichia coli. Antimicro
Brown, A. G. / 1976 / Naturally-occurring β-lactamase inhibitors with antibacterial activity / J. Antibiot 29 : 668 ~ 669
Butterworth, D. / 1979 / Olivanic acids, a family of β-lactam antibiotics with β-lactamase inhibitory properties produced by Streptomyces species. I. Detection, properties
Cole, C. N. / 1998 / Nucleocytoplasmic transport: Driving and directing transport. Curr / Biol 8 : R368 ~ R372
Doran, J. L. / 1990 / Isolation and characterization of a β-lactamase-inhibitory protein from Streptomyces clavuligerus and cloning and analysis of the corresponding gene /
Brown, A. G. / 1976 / Naturally-occurring β-lactamase inhibitors with antibacterial activity / J. Antibiot 29 : 668 ~ 669
Butterworth, D. / 1979 / Olivanic acids, a family of β-lactam antibiotics with β-lactamase inhibitory properties produced by Streptomyces species. I. Detection, properties
Cole, C. N. / 1998 / Nucleocytoplasmic transport: Driving and directing transport. Curr / Biol 8 : R368 ~ R372
Doran, J. L. / 1990 / Isolation and characterization of a β-lactamase-inhibitory protein from Streptomyces clavuligerus and cloning and analysis of the corresponding gene /
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