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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제16권 제12호
- 발행연도
- 2006.1
- 수록면
- 1,940 - 1,946 (7page)
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초록· 키워드
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The influence of environmental conditions on theganoderic acid (GA) content in the fungus Ganoderma lucidumwas investigated using a one-factor-at-a-time design andorthogonal design. Among the various medium componentsexamined, sucrose, soybean powder or peptone, ferrous sulfate,and pH 6.0were the most suitable carbon source (factor A),nitrogen source (factor B), mineral source (factor C), andfactor-at-a-time design. According to the orthogonal design, theorder of effect for the four factors on the GA content wasA>C>D>B. The best level of factor A was A2 (sucrose) witha value of +0.34 mg/10 mg DW. The optimal treatmentcombination was A2B1C3D1 with which the GA contentreached up to 2.63±0.01 mg/100 mg DW. The interactionsmineral ion and the pH were both highly significant (P<0.01).The highest interaction effect was (B2×D2) with a value of+0.19 mg/10 mg DW, which was higher than the level effectvalue for B2 (peptone) and D2 (pH 5.0). Therefore, the resultsproved that interactions betwen factors cannot be ignored.The results also indicated the importance of the interactionsbetwen the factors, which may help to understand theexpression and regulation of the key enzymes involved.
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참고문헌 (22)
참고문헌 신청
Charonnet, C. O / 1999 / Calcium effect on the mycelial cell walls of Botrytis cinerea / Phytochemistry 52 : 967 ~ 976
Cheng, R. Y / 1990 / Research progress on the chemical component of Ganoderma lucidum triterpenoid / Acta Pharmaceut. Sin. (in Chinese) 25 : 940 ~ 953
Ding, F. P / 2001 / Optimization of fermentation conditions for preparation of polygalacturonic acid transeliminase by Erwinia carotovora IFO3830 / Biotechnol. Prog. 17 : 311
Fang, Q. H / 2002 / Effect of initial pH on production of ganoderic acid and polysaccharide by submerged fermentation of Ganoderma lucidum / Process Biochem. 37 : 769 ~ 774
Fang, Q. H / 2002 / Significance of inoculation density control in production of polysaccharide and ganoderic acid by submerged culture of Ganoderma lucidum / Process Biochem
Cheng, R. Y / 1990 / Research progress on the chemical component of Ganoderma lucidum triterpenoid / Acta Pharmaceut. Sin. (in Chinese) 25 : 940 ~ 953
Ding, F. P / 2001 / Optimization of fermentation conditions for preparation of polygalacturonic acid transeliminase by Erwinia carotovora IFO3830 / Biotechnol. Prog. 17 : 311
Fang, Q. H / 2002 / Effect of initial pH on production of ganoderic acid and polysaccharide by submerged fermentation of Ganoderma lucidum / Process Biochem. 37 : 769 ~ 774
Fang, Q. H / 2002 / Significance of inoculation density control in production of polysaccharide and ganoderic acid by submerged culture of Ganoderma lucidum / Process Biochem
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