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논문 기본 정보
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- 저자정보
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- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제17권 제1호
- 발행연도
- 2007.1
- 수록면
- 21 - 28 (8page)
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The crude biopolymer (AS-S1) and endo-biopolymer (AS-S2) were isolated from the dry stem bark ofAcanthopanax sessiliflorus and tested for anti complementactivity. The two potent anticomplement biopolymers, AS-1and AS-2-Fr.I, were isolated by the combination of ion-endo-biopolymers (AS-S2). The anticomplement activity ofAS-1.(MW 12 kDa) and AS-2-Fr.I (MW 180 kDa) were foundto be 84.4% and 10.0%, respectively, at the concentration of25 g/ml. Activated pathway of the complement systemoccured in both classical and alternative pathways, asevidenced by crossed imunoelectrophoresis (CIEP), wherea major pathway was detected to be the classical one. It wasfound that the anticomplement activities of the periodatedigested biopolymers of AS-1 and AS-2-Fr.I were decreasedvery little. The AS-1 contained 2,4,6-tri-O-methyl-D-glucitol,2,3,6-tri-O-methyl-D-glucitol, and 2,3,6-tri-O-methyl-D-galacitol, which indicated that AS-1 contained a (1→3), (1→4)-linked glucopyranosyl residue and a (1→4)-linked galactosylresidue. AS-2-Fr.I contained mainly 2,4-di-O-methyl-D-mannitoland 2,3,4-tri-O-methyl-D-galacitol, which contained (1→3),(1→6) linked mannosyl and (1→6) linked galactosyl residues.
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참고문헌 (27)
참고문헌 신청
A / 1956 / Colorimetric method for determination of sugar and related substance : 350 ~ 356
A / 1974 / Activation of the alternative pathway of human complement b
Abul, K. A / 2003 / Cellular and Molecular Immunology : 327 ~
Bartolome, A. P / 1995 / Polysaccharides from the cell walls of pineapple fruit 43 : 608 ~ 612
Davydov, M / 2000 / Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Areliaceae) as an adoptogen: A closer look 72 : 345 ~ 393
A / 1974 / Activation of the alternative pathway of human complement b
Abul, K. A / 2003 / Cellular and Molecular Immunology : 327 ~
Bartolome, A. P / 1995 / Polysaccharides from the cell walls of pineapple fruit 43 : 608 ~ 612
Davydov, M / 2000 / Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Areliaceae) as an adoptogen: A closer look 72 : 345 ~ 393
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