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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제18권 제2호
- 발행연도
- 2008.1
- 수록면
- 365 - 368 (4page)
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Calcium entry through Cav3.2 Ca2+ channels plays essential
roles for various physiological events including thalamic
oscillation, muscle contraction, hormone secretion, and
sperm acrosomal reaction. In this study, we examined how
protein tyrosine phosphatases or protein tyrosine kinases
affect Cav3.2 Ca2+ channels reconstituted in Xenopus oocytes.
We found that Cav3.2 channel activity was reduced by
25% in response to phenylarsine oxide (tyrosine phosphatase
inhibitor), whereas it was augmented by 19% in response
to Tyr A47 or herbimycin A (tyrosine kinase inhibitors).
However, other biophysical properties of Cav3.2 currents
were not significantly changed by the drugs. These results
imply that Cav3.2 channel activity is capable of being
increased by activation of tyrosine phosphatases, but is
decreased by activation of tyrosine kinases.
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참고문헌 (23)
참고문헌 신청
[학술지(정기
Akamatsu, S. / 2004 / Hepatoprotective effect of extracts from Lentinus edodes mycelia on dimethylnitrosamine-induced liver injury. Biol. Pharm / Bull 27 : 1957 ~ 1960
Allavena, P. / 2004 / From pattern recognition receptor to regulator of homeostasis: The double-faced macrophage mannose receptor. Crit. Rev / Immunol 24 : 179 ~ 192
Borchers, A. T. / 1999 / Mushrooms, tumors, and immunity. Proc. Soc. Exp. Biol / Med 221 : 281 ~ 293
Brown, G. D. / 2002 / Dectin-1 is a major beta-glucan receptor on macrophages. J. Exp / Med 196 : 407 ~ 412
Akamatsu, S. / 2004 / Hepatoprotective effect of extracts from Lentinus edodes mycelia on dimethylnitrosamine-induced liver injury. Biol. Pharm / Bull 27 : 1957 ~ 1960
Allavena, P. / 2004 / From pattern recognition receptor to regulator of homeostasis: The double-faced macrophage mannose receptor. Crit. Rev / Immunol 24 : 179 ~ 192
Borchers, A. T. / 1999 / Mushrooms, tumors, and immunity. Proc. Soc. Exp. Biol / Med 221 : 281 ~ 293
Brown, G. D. / 2002 / Dectin-1 is a major beta-glucan receptor on macrophages. J. Exp / Med 196 : 407 ~ 412
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