지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제16권 제6호
- 발행연도
- 2006.1
- 수록면
- 933 - 938 (6page)
이용수
초록· 키워드
오류제보하기
Decaprenyl diphosphate synthase (DPS) is thekey enzyme for the production of coenzyme Q10 (CoQ10). Adps gene from Sinorhizobium meliloti KCM 11232 (IFO14782) was isolated by PCR and then cloned in Escherichiacoli. DNA sequencing analysis revealed an open readingframe of 1,017 bp encoding a 338-amino-acid protein. Theprotein was identical at the 98% level to the putative octaprenyldiphosphate synthase (IspB) of S. meliloti 1021. The deducedamino acid sequence included the DDxxD domains conservedin the majority of the prenyl diphosphate synthases. Heterologousexpression in E. coli BL21(DE3) was carried out, and theCoQ10 produced was then analyzed by HPLC. E. coliBL21(DE3) harboring the dps gene from S. meliloti producedCoQ10 in addition to endogenous coenzyme Q8 (CoQ8), whereaswild-type E. coli BL21(DE3) host did not have the ability ofproducing CoQ10. The results sugest that the putative dpsfrom S. meliloti KCTC 2353 encoded the DPS.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Alleva, R / 2001 / Coenzyme Q blocks biochemical but not receptor-mediated apoptosis by increasing mitochondrial antioxidant protection. / FEBS Lett. 503 : 46 ~ 50
Asai, K / 1994 / The identification of Escherichia coli ispB (cel) gene encoding the octaprenyl diphosphate synthase / Biochem. Biophys. Res. Commun. 202 : 340 ~ 345
Chen, A / 1994 / Isoprenyl diphosphate synthases: Protein sequence comparisons, a phylogenetic tree, and predictions of secondary structure / Protein Sci. 3 : 600 ~ 607
Ernster, L / 1995 / Biochemical, physiological and medical aspects of ubiquinone function / Biochim. Biophys. Acta 1271 : 195 ~ 204
Joly, A / 1993 / Effect of site-directed mutagenesis of conserved aspartate and arginine residues upon farnesyl diphosphate synthase activity / J. Biol. Chem. 268
Asai, K / 1994 / The identification of Escherichia coli ispB (cel) gene encoding the octaprenyl diphosphate synthase / Biochem. Biophys. Res. Commun. 202 : 340 ~ 345
Chen, A / 1994 / Isoprenyl diphosphate synthases: Protein sequence comparisons, a phylogenetic tree, and predictions of secondary structure / Protein Sci. 3 : 600 ~ 607
Ernster, L / 1995 / Biochemical, physiological and medical aspects of ubiquinone function / Biochim. Biophys. Acta 1271 : 195 ~ 204
Joly, A / 1993 / Effect of site-directed mutagenesis of conserved aspartate and arginine residues upon farnesyl diphosphate synthase activity / J. Biol. Chem. 268
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Increase of CoQ10 Production Level by the Coexpression of DecaprenylDiphosphate Synthase and 1-Deoxy-D-xylulose 5-Phosphate Synthase from Rhizobium radiobacter ATCC 4718
Journal of Microbiology and Biotechnology
2007 .01
-
Neurospora crassa coq-1 and coq-7 genes can complement Saccharomyces cerevisiae coq1 and coq7 mutants
한국생명과학회 심포지움
2003 .05
-
Solubility Enhancing Effect of Insoluble Drugs by Complex with Succinoglycan Oligosaccharides Originated from Sinorhizobium meliloti
한국미생물학회 학술대회논문집
2012 .05
-
Biotin Labeling of Succinoglycan and the Monomers Isolated from Sinorhizobium meliloti for the Neoglycoconjugate with Streptavidin
한국미생물학회 학술대회논문집
2012 .05
-
Neurospora crassa 유전자에 의한 Saccharomyces cerevisiae coq7 돌연변이의 회복
생명과학회지
2003 .12
-
CoQ10 생성 세균의 선별 및 발효조건 최적화
미생물학회지
2010 .03
-
Effect of Limited Oxygen Supply on Coenzyme Q10 Production and Its Relation to Limited Electron Transfer and Oxidative Stress in Rhizobium radiobacter T6102
Journal of Microbiology and Biotechnology
2010 .01
-
Rhizobium meliloti 102F51 Mutants Defective in Heme Synthesis
미생물학회지
1986 .06
-
Association of Colony Morphology with Coenzyme Q10 Production and Its Enhancement from Rhizobium radiobacter T6102W by Addition of Isopentenyl Alcohol as a Precursor
Journal of Microbiology and Biotechnology
2012 .01
-
Rhizobium meliloti와 Bradyrhizobium japonicum의 Ribosomal RNA 유전자에 관한 연구
미생물학회지
1988 .12
-
Effects of Hg and Cd on the Growth and Nitrogen Fixation of Melilotus suaveolens seedlings
한국동물학회 학술대회
1996 .01
-
cDNA Isolation and Characterization of (+)-Germacrene A Synthase from Ixeris dentata form. albiflora Hara
식물학회지
2005 .01
-
대장균 세포 내 다양한 외부 스트레스에 대한 DPS 단백질의 생리적 기능
생명과학회지
2013 .04
-
Thymine-Starvation Up-Regulates a Region of the Arabidopsis thaliana Chromosome III Containing Both the UMP Synthase Gene and a Proximal Gene Encoding a Novel F-Box Protein
식물학회지
2002 .01
-
Effect of coenzyme Q10 and Ardisia japonica Blume on plasma and liver lipids, platelet aggregation, and erythrocyte Na efflux channels in simvastatin-treated guinea pigs
Nutrition Research and Practice
2012 .10
-
Effect of coenzyme Q10 and Ardisia japonica Blume on plasma and liver lipids, platelet aggregation, and erythrocyte Na efflux channels in simvastatin-treated guinea pigs
Nutrition Research and Practice
2012 .10
-
Molecular Cloning and Co-Expression of Phytoene Synthase Gene from Kocuria gwangalliensis in Escherichia coli
Journal of Microbiology and Biotechnology
2015 .01
-
Reciprocal Regulation of Sucropse phosphate synthase and Sucrose synthase Gene Expression from Tomato Roots by Salt Stress
한국동물학회 학술대회
1998 .01
-
CHARACTERIZATION OF THE GROUPS Dp+1(2) AND Dp+1(3) USING ORDER COMPONENTS
대한수학회지
2010 .01
-
Nucleotide Sequence Analysis of a Second Set of the Polyketide Synthase β-Ketoacyl synthase and Chain Length Factor Genes from the Salinomycin-producing Streptomyces albus
The Journal of Microbiology
1997 .03
이 논문의 저자 정보
최근 본 자료
댓글(0)
0