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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제18권 제8호
- 발행연도
- 2008.1
- 수록면
- 1,353 - 1,356 (4page)
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RNase E (Rne) plays a major role in the decay and processing of numerous RNAs in E. coli, and protein inhibitors of RNase E, RraA and RraB, have recently been discovered. Here, we report that coexpression of RraA or RraB reduces the ribonucleolytic activity in rne-deleted E. coli cells overproducing RNase ES, a Streptomyces coelicolor functional ortholog of RNase E, and consequently rescues these cells from growth arrest.
These findings suggest that the regulators of ribonuclease activity have a conserved intrinsic property that effectively acts on an RNase E-like enzyme found in a distantly related bacterial species.
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참고문헌 (17)
참고문헌 신청
Carpousis, A. J. / 2007 / The RNA degradosome of Escherichia coli: An mRNA-degrading machine assembled on RNase E. Annu. Rev / Microbiol 61 : 71 ~ 87
Gao, J. / 2006 / Differential modulation of E. coli mRNA abundance by inhibitory proteins that alter the composition of the degradosome. Mol / Microbiol 61 : 394 ~ 406
Hagege, J. M. / 1997 / A developmentally regulated Streptomyces endoribonuclease resembles ribonuclease E of Escherichia coli. Mol / Microbiol 25 : 1077 ~ 1090
Jain, C. / 1995 / Autoregulation of RNase E synthesis in Escherichia coli. Nucleic Acids Symp / Ser 33 : 85 ~ 88
Jain, C. / 2002 / Consequences of RNase E scarcity in Escherichia coli. Mol / Microbiol 43 : 1053 ~ 1064
Gao, J. / 2006 / Differential modulation of E. coli mRNA abundance by inhibitory proteins that alter the composition of the degradosome. Mol / Microbiol 61 : 394 ~ 406
Hagege, J. M. / 1997 / A developmentally regulated Streptomyces endoribonuclease resembles ribonuclease E of Escherichia coli. Mol / Microbiol 25 : 1077 ~ 1090
Jain, C. / 1995 / Autoregulation of RNase E synthesis in Escherichia coli. Nucleic Acids Symp / Ser 33 : 85 ~ 88
Jain, C. / 2002 / Consequences of RNase E scarcity in Escherichia coli. Mol / Microbiol 43 : 1053 ~ 1064
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