지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 153 - 159 (7page)
이용수
초록· 키워드
오류제보하기
Recombinant Escherichia coli BLR(DE3) harboring the hemA
gene from Rhodobacter capsulatus under the control of a constitutive promoter, which we constructed previously,
was used for the extracellular production of 5-aminolevulinic acid (ALA). The effects of several factors
on ALA production were investigated in flask culture. ALA production by the recombinant E. coli was more
efficient at 30℃ than 37℃. The glycine concentration had an important effect on cell growth. Glycine and
succinic acid concentration of 5-10 and 10-20 g/L, respectively, resulted in high ALA production. In addition,
the partial replacement of succinic acid by sodium glutamate increased the ALA production. The ALA production
was inhibited by the presence of glucose in the medium. Using the optimal conditions, an ALA concentration
of 8.2 g/L was achieved in jar fermentation without an added inducer or ALA dehydratase inhibitor;
this is the highest reported concentration.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Avissar, Y. J / 1989 / Identification of the enzymatic basis for a-aminolevulinic acid auxotrophy in a hemA mutant of Escherichia coli / J. Bacteriol 171 : 2919 ~ 2924
Beale, S. J / 1974 / The Biosynthesis of δ-aminolevulinic acid in higher plants. II. Formation of 14C-δ-aminolevulinic acid from labeled precursors in greening plant tissue
Berg, K / 2005 / Porphyrin-related photosensitizers for cancer imaging and therapeutic applications / J. Microsc. 218 : 133 ~ 147
Bykhovsky, V. Y / 1997 / The crucial contribution of starved resting cells to the elucidation of the pathway of vitamin B12 biosynthesis / Critical Rev. Biotechnol 17 (1) : 2
Choi, C / 1999 / Optimization of extracellular 5-aminolevulinic acid production from Escherichia coli transformed with ALA synthase gene of Bradyrhizobium japonicum / Biotech
Beale, S. J / 1974 / The Biosynthesis of δ-aminolevulinic acid in higher plants. II. Formation of 14C-δ-aminolevulinic acid from labeled precursors in greening plant tissue
Berg, K / 2005 / Porphyrin-related photosensitizers for cancer imaging and therapeutic applications / J. Microsc. 218 : 133 ~ 147
Bykhovsky, V. Y / 1997 / The crucial contribution of starved resting cells to the elucidation of the pathway of vitamin B12 biosynthesis / Critical Rev. Biotechnol 17 (1) : 2
Choi, C / 1999 / Optimization of extracellular 5-aminolevulinic acid production from Escherichia coli transformed with ALA synthase gene of Bradyrhizobium japonicum / Biotech
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Extracellular 5-Aminolevulinic Acid Production by Escherichia coli Containingthe Rhodopseudomonas palustris KUGB306 hemA Gene
Journal of Microbiology and Biotechnology
2008 .01
-
포유류 세포주에서 δ-Aminolevulinic acid (ALA)의 세포증식과 사멸에 미치는 영향분석
분석과학
2014 .10
-
Process Strategies to Enhance the Production of 5-Aminolevulinic Acid with Recombinant E. coli
Journal of Microbiology and Biotechnology
2004 .01
-
Cloning and Expression of the Rhodobacter capsulatus hemA Gene in E. colifor the Production of 5-Aminolevulinic Acid
Journal of Microbiology and Biotechnology
2004 .01
-
5-Aminolevulinic Acid Biosynthesis in Escherichia coli CoexpressingNADP-dependent Malic Enzyme and 5-Aminolevulinate Synthase
Journal of Microbiology and Biotechnology
2007 .01
-
The Effects of ALA-PDT on Leukemia Cells and Hepatoma Cells
Journal of photoscience : an international journal officail organ of the korean society of photoscience
2002 .01
-
Bacillus cereus 1-1 균주의 5-Aminolevulinic Acid (ALA) 생산
미생물학회지
2007 .12
-
Optimization of Influencing Factors on Biomass Accumulation and 5-Aminolevulinic Acid (ALA) Yield in Rhodobacter sphaeroides Wastewater Treatment
Journal of Microbiology and Biotechnology
2015 .01
-
Silencing of ALA dehydratase affects ALA-photodynamic therapy efficacy in K562 erythroleukemic cells
Photochemical & photobiological sciences : an international journal
2009 .01
-
In Vitro expression of protoporphyrin IX induced by 5-aminolevulinic acid (ALA) in human cancer and normal cells
한국생명과학회 심포지움
2006 .09
-
Protective effects of perilla oil and alpha linolenic acid on SH-SY5Y neuronal cell death induced by hydrogen peroxide
Nutrition Research and Practice
2018 .04
-
Protective effects of perilla oil and alpha linolenic acid on SH-SY5Y neuronal cell death induced by hydrogen peroxide
Nutrition Research and Practice
2018 .04
-
Fabrication of an α-lipoic acid-eluting poly-(D,L-lactide-cocaprolactone) cuff for the inhibition of neointimal formation
Experimental and Molecular Medicine
2009 .01
-
(InAs)n(AlAs)n 단주기 초결자의 MBE 성장과 X선회절
Applied Science and Convergence Technology
1992 .10
-
Apoptotic Signaling Cascade of 5-aminolaevulinic Acid-based Photodynamic Therapy in Human Promyelocytic Leukemia HL-60 Cells
Journal of photoscience : an international journal officail organ of the korean society of photoscience
2002 .01
-
Bandgap Engineering of self - assembled InAs quantum dots with a thin AlAs barrier
한국진공학회 학술발표회초록집
2003 .08
-
Analysis of Heme Biosynthetic Pathways in a Recombinant Escherichia coli
Journal of Microbiology and Biotechnology
2015 .01
-
Production of Lipocortin-11-185 Using A Recombinant of Escherichia coli.
The Journal of Microbiology
1997 .06
이 논문의 저자 정보
최근 본 자료
댓글(0)
0