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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 221 - 225 (5page)
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초록· 키워드
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Amyloidosis is an abnormal extracellular deposit of amyloid in various organs of the body. Amyloid goiter, defined by a clinically detectable thyroid enlargement due to amyloid deposition, is a rare cause of hyperthyroidism. We report the case of amyloid goiter mimicking Graves’ disease in a 62-year-old woman.
Graves’ disease was diagnosed by diffuse goiter, hyperthyroidism, and positive TSH receptor antibody. Total thyroidectomy was planned due to progression of Graves’ disease and respiratory distress. At surgery thyroid gland was very friable and fragmented like cobblestones when grasped with forceps. A diagnosis of amyloid goiter was established by the presence of diffuse amyloid deposits in the parafollicular areas. After systemic evaluation for amyloidosis, coexisting both multiple myeloma and systemic amyloidosis involving kidney and heart were detected. She underwent palliative chemotherapy but disease progressed. Amyloid goiter might be suspected in patient with thyroid enlargement and concomitant systemic disease such as renal or heart failure.
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등록된 정보가 없습니다.
참고문헌 (9)
참고문헌 신청
Chung R / 2013 / Primary amyloid goiter and review of imaging characteristics / Ultrasound 21 (2) : 98 ~ 101
Dinner S / 2013 / The prognostic value of diagnosing concurrent multiple myeloma in immunoglobulin light chain amyloidosis / Br J Haematol 161 (3) : 367 ~ 372
Gertz MA / 2014 / Immunoglobulin light chain amyloidosis: 2014update on diagnosis, prognosis, and treatment / Am J Hematol 89 (12) : 1132 ~ 1140
Kimura H / 1997 / Thyroid dysfunction in patients with amyloid goitre / Clin Endocrinol (Oxf) 46 (6) : 769 ~ 774
Kyle RA / 1995 / Primary systemic amyloidosis: clinical and laboratory features in 474 cases / Semin Hematol 32 (1) : 45 ~ 59
Dinner S / 2013 / The prognostic value of diagnosing concurrent multiple myeloma in immunoglobulin light chain amyloidosis / Br J Haematol 161 (3) : 367 ~ 372
Gertz MA / 2014 / Immunoglobulin light chain amyloidosis: 2014update on diagnosis, prognosis, and treatment / Am J Hematol 89 (12) : 1132 ~ 1140
Kimura H / 1997 / Thyroid dysfunction in patients with amyloid goitre / Clin Endocrinol (Oxf) 46 (6) : 769 ~ 774
Kyle RA / 1995 / Primary systemic amyloidosis: clinical and laboratory features in 474 cases / Semin Hematol 32 (1) : 45 ~ 59
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