지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Background: The aim of this study was to analyze regional differences in the stress distribution within the distal femur in advanced osteoarthritis (OA). Methods: Distal femoral specimens with primary OA were obtained from 10 female donor cadavers (mean age, 65 years; range, 53-79). As controls, distal femurs without OA were obtained from 10 age- and sex-matched female cadavers (mean age, 67 years; range, 58-81). The articular surface of the distal femur was divided into anterior, middle, and posterior regions on each condyle. Mechanical properties and microstructure were assessed for each region with micro-computed tomography and finite element model analysis. Results: The control group showed differences in stress distribution among 6 regions on the distal femur (P=0.037), but there was no regional difference in stress distribution among 6 regions on the distal femur in the advanced OA group (P=0.179). Conclusions: Regional stress distribution in the distal femur was different between advanced OA and normal groups. There were no regional differences in stress distribution in the advanced OA group. Altered loading patterns, bone remodeling, and chemical composition will affect stress distribution.
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참고문헌 (16)
참고문헌 신청
Neogi T / 2012 / Clinical significance of bone changes in osteoarthritis / Ther Adv Musculoskelet Dis 4:259~267
Rubin CT / 1984 / Regulation of bone formation by applied dynamic loads / J Bone Joint Surg Am 66:397~402
Li B / 1997 / Composition and mechanical properties of cancellous bone from the femoral head of patients with osteoporosis or osteoarthritis / J Bone Miner Res 12:641~651
Brittberg M / 2003 / Evaluation of cartilage injuries and repair / J Bone Joint Surg Am 85-A(Suppl 2):58~69
Niebur GL / 2000 / High-resolution finite element models with tissue strength asymmetry accurately predict failure of trabecular bone / J Biomech 33:1575~1583
Rubin CT / 1984 / Regulation of bone formation by applied dynamic loads / J Bone Joint Surg Am 66:397~402
Li B / 1997 / Composition and mechanical properties of cancellous bone from the femoral head of patients with osteoporosis or osteoarthritis / J Bone Miner Res 12:641~651
Brittberg M / 2003 / Evaluation of cartilage injuries and repair / J Bone Joint Surg Am 85-A(Suppl 2):58~69
Niebur GL / 2000 / High-resolution finite element models with tissue strength asymmetry accurately predict failure of trabecular bone / J Biomech 33:1575~1583
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