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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 70 - 75 (6page)
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초록· 키워드
오류제보하기
Objective: Diseases of the respiratory system are one of the main causes of death and include situation such as chronic obstructive pulmonary disease, pneumonia or asthma. Medicinal plants have beneficial effects on multiple diseases include respiratory disorders like asthma and bronchitis. The aim of this study was to evaluate the effects of U. dioica and L. Album on tracheal smooth muscle contraction. Material and methods: Hydroalcoholic extracts of L. Album and U. Dioica aerial parts were prepared by maceration method and standardized based on their total phenol content. The effect of the extracts on the KCl-induced contraction of rat trachea was examined in an organ bath chamber. Data was analyzed with spss software 22. Results: The extract of L. Album (5 mg/ml), similar to theophylline (20 mM), significantly reduced the KCl-induced tracheal contraction. On the other hand, U. Dioica (1 mg/ml and 5 mg/ml) augmented the KCl-induced contraction. Conclusion: The relaxant effect of L. Album on the trachea makes it as a candidate for the managing patients with asthma and obstructive pulmonary diseases. But because of U. Dioica potential constrictive effect on the trachea it is suggested that patients avoid consuming it.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
http://www.who.int/respiratory/asthma/en/
Banerji D / 2014 / Dual bronchodilation for the treatment of chronic obstructive pulmonary disease: a review of the latest clinical data / Clin Invest 4:511~533
Doeing DC / 2013 / Airway smooth muscle in the pathophysiology and treatment of asthma / J Appl Physiol 114:834~843
Bozzola E / 2013 / Safety and potential side effects of 2-agonists: a still debated question / Int J Pediatr Child Health 1:4~10
Haney S / 2006 / Recovery from bronchoconstriction and bronchodilator tolerance / Clin Rev Allergy Immunol 31:181~196
Banerji D / 2014 / Dual bronchodilation for the treatment of chronic obstructive pulmonary disease: a review of the latest clinical data / Clin Invest 4:511~533
Doeing DC / 2013 / Airway smooth muscle in the pathophysiology and treatment of asthma / J Appl Physiol 114:834~843
Bozzola E / 2013 / Safety and potential side effects of 2-agonists: a still debated question / Int J Pediatr Child Health 1:4~10
Haney S / 2006 / Recovery from bronchoconstriction and bronchodilator tolerance / Clin Rev Allergy Immunol 31:181~196
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