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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 5 - 14 (10page)
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Objective : This study was undertaken to determine the effect of Whallak-tang on expression of CD/cytokine Genes. Methods : The expression of CD/Cytokine Genes were examined by cDNA microarray using the human mast cell line(HMC-l). Results : The expression of ATP5F1, FLJ20671, unknown, KIAA0342, OAS2, unknown genes were increased in 200～300% range. The expression of unknown, MDS006, IFITM1, MRPL3, ZNF207, FTH1, FBP1, NRGN, NR1H2, KIAA0747 genes were decreased in 0～33% range. Conclusion : These results would provide important basic data on the possibility of the clinical treatment of Whallak-tang in musculoskeletal disease.
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참고문헌 (41)
참고문헌 신청
Shih DQ. / 1999 / Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice / Proc Natl Acad Sci U S A 96(18):10152~10157
Baudier J. / 1991 / Purification and characterization of a brain-specific protein kinase C substrate, neurogranin (p17):identification of a consensus amino acid sequence between neurogranin and neuromodulin (GAP43) that corresponds to the protein kinase C phosphorylation site and the calmodulin-binding domain / J. B iol. Chem 266:229~237
Martinez de Arrieta C. / 1997 / Structure, organization, and chromosomal mapping of the human neurogranin gene (NRGN) / Genomics 41:243~249
Janowski B A. / 1999 / , Kliewer S A, Corey E J, Mangelsdorf D J. Structural requirements of ligands for the oxysterol liver X receptors LXR-alpha and LXR-beta / Proc. Nat. Acad. Sci 96:266~271
Shinar D M. / 1994 / NER, a new member of the gene family encoding the human steroid hormone nuclear receptor / Gene 147:273~276
Baudier J. / 1991 / Purification and characterization of a brain-specific protein kinase C substrate, neurogranin (p17):identification of a consensus amino acid sequence between neurogranin and neuromodulin (GAP43) that corresponds to the protein kinase C phosphorylation site and the calmodulin-binding domain / J. B iol. Chem 266:229~237
Martinez de Arrieta C. / 1997 / Structure, organization, and chromosomal mapping of the human neurogranin gene (NRGN) / Genomics 41:243~249
Janowski B A. / 1999 / , Kliewer S A, Corey E J, Mangelsdorf D J. Structural requirements of ligands for the oxysterol liver X receptors LXR-alpha and LXR-beta / Proc. Nat. Acad. Sci 96:266~271
Shinar D M. / 1994 / NER, a new member of the gene family encoding the human steroid hormone nuclear receptor / Gene 147:273~276
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