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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 857 - 864 (8page)
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Purpose: The aim of this study was to identify the associations among physical activity, disease activity, and organ damage in patientswith systemic lupus erythematosus (SLE). Materials and Methods: A total of 415 patients with SLE were consecutively enrolled from the KORean lupus Network (KORNET)registry. This registry assessed clinical features, disease activity [Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K)], and organ damage [Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) Damage Index (SDI)] upon enrollment in the study. Self-reported physical activity was measured by the International PhysicalActivity Questionnaire. Statistical analyses were conducted using the Mann-Whitney U test and multivariate logistic regressionanalysis. Results: A significant difference in vigorous activity was noted between patients with lupus nephritis (LN) (n=93) and those withoutLN (n=322) (p=0.012), but not in moderate and walking activities. In contrast, no differences in physical activity, walking,moderate, and vigorous intensity, according to SLEDAI-2K and SDI were found. In addition to younger age (p=0.032), high physicalcomponent summary of SF-36 (p=0.004) and SLEDAI-2K (p=0.038), and less vigorous physical activity were associated withLN (p=0.024). However, cardiovascular disease was not associated with physical activity in SLE patients. Conclusion: This study showed that patients with LN had less vigorous physical activity than patients without LN. The results suggestthat lupus nephritis might be associated with physical activity.
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참고문헌 (35)
참고문헌 신청
Tsokos GC / 2011 / Systemic lupus erythematosus / N Engl J Med 365:2110~2121
Katz P / 2012 / Physical activity, obesity, and cognitive impairment among women with systemic lupus erythematosus / Arthritis Care Res (Hoboken) 64:502~510
Rodriguez Huerta MD / 2016 / Healthy lifestyle habits for patients with systemic lupus erythematosus: a systemic review / Semin Arthritis Rheum 45:463~470
Pettersson S / 2015 / Lifestyle habits and fatigue among people with systemic lupus erythematosus and matched population controls / Lupus 24:955~965
O'Dwyer T / 2017 / Exercise and physical activity in systemic lupus erythematosus: a systematic review with metaanalyses / Semin Arthritis Rheum 47:204~215
Katz P / 2012 / Physical activity, obesity, and cognitive impairment among women with systemic lupus erythematosus / Arthritis Care Res (Hoboken) 64:502~510
Rodriguez Huerta MD / 2016 / Healthy lifestyle habits for patients with systemic lupus erythematosus: a systemic review / Semin Arthritis Rheum 45:463~470
Pettersson S / 2015 / Lifestyle habits and fatigue among people with systemic lupus erythematosus and matched population controls / Lupus 24:955~965
O'Dwyer T / 2017 / Exercise and physical activity in systemic lupus erythematosus: a systematic review with metaanalyses / Semin Arthritis Rheum 47:204~215
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