지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 832 - 837 (6page)
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초록· 키워드
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Purpose: This study examined the sparing effect of sufentanil on the median effectiveconcentration (EC50) of epidural ropivacaine in elderly patients undergoing elective transurethral resection of prostate (TURP). Materials and Methods: This was a prospective randomized double-blind dose-response study. Fifty eight elderlypatients with American Society of Anesthesiologists physical status I‒II who were scheduled for TURP surgery under epidural anesthesia were randomly allocatedto a group receiving 15 mL of ropivacaine (group R) or a group receiving ropivacaine plus 5 μg of sufentanil (group RS). The concentration of ropivacaine was determined by a Dixon’s up-and-down sequential allocation. The first participantreceived 0.3% of ropivacaine in both groups and subsequent concentrations were determined by the response of the previous patient in the same group. The EC50 of epidural ropivacaine was analyzed using the Dixon and Massey method. Results: The EC50 of ropivacaine during TURP surgery was 0.186% (95% confidenceinterval, 0.173‒0.200%) in group R, and 0.136% (95% confidence interval, 0.127‒0.144%) in group RS (p<0.01). No differences in Bromage scale of motor block examination and the onset time of sensory block were observed. Conclusion:Administration of 5 μg of epidural sufentanil caused a 37% reduction in the EC50 of epidural ropivacaine in elderly patients who underwent TURP surgery. Thus, sufentanil addition during surgery of TURP can decrease the dose of ropivacaineanesthesia required.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Braga Ade F / 2003 / Sufentanil added to hyperbaric bupivacaine for subarachnoid block in Caesarean section / Eur J Anaesthesiol 20 : 631 ~ 635
Buyse I / 2007 / Effect of sufentanil on minimum local analgesic concentrations of epidural bupivacaine, ropivacaine and levobupivacaine in nullipara in early labour / Int J
Chaudhary A / 2014 / Efficacy of spinal ropivacaine versus ropivacaine with fentanyl in transurethral resection operations / Saudi J Anaesth 8 : 88 ~ 91
Chen X / 2010 / Intrathecal sufentanil decreases the median effective do
Dahlgren G / 1997 / Intrathecal sufentanil, fentanyl, or placebo added to bupivacaine for cesarean section / Anesth Analg 85 : 1288 ~ 1293
Buyse I / 2007 / Effect of sufentanil on minimum local analgesic concentrations of epidural bupivacaine, ropivacaine and levobupivacaine in nullipara in early labour / Int J
Chaudhary A / 2014 / Efficacy of spinal ropivacaine versus ropivacaine with fentanyl in transurethral resection operations / Saudi J Anaesth 8 : 88 ~ 91
Chen X / 2010 / Intrathecal sufentanil decreases the median effective do
Dahlgren G / 1997 / Intrathecal sufentanil, fentanyl, or placebo added to bupivacaine for cesarean section / Anesth Analg 85 : 1288 ~ 1293
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