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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 58 - 64 (7page)
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Purpose: The aim of this study is to compare the clinical and urodynamic characteristics of urinary disorders in multiple sclerosis (MS) patients in a geriatric population with a nongeriatric population. Methods: This study was conducted retrospectively between 2010 and 2016. Each patient with MS aged 65 and older was matched with 2 patients with MS aged less than 65 in sex, form of MS, and Expended Disability Status Scale (EDSS). Demographic data, urinary symptoms, treatment, quality of life, repercussion of lower urinary tract symptoms on daily life activities and psychological state and urodynamic parameters were collected. Differences between the 2 populations were evaluated using Student test, chi-square, or Fischer tests. Results: Twenty-four patients with MS aged 65 and older (mean age, 69.8 years) were matched with 48 patients aged less than 65 years (mean age, 49.4 years). Maximum urethral closure pressure was lower in the elderly population than in the nongeriatric population (mean±standard deviation [SD]: 35.6±18.5 cm H2O vs. 78.2±52.3 cm H2O, P<0.001). In the male population, there was no statistical difference in any other clinical or urodynamic endpoints. In the female population, voiding symptoms was more described in the nongeriatric population (Urinary Symptom Profile low stream: 3.4±3.5 vs. 1.7±2.4, P=0.04), geriatric population had less urinary treatment (P=0.05). LUTS had less impact on quality of life (Qualiveen: 1.4±1.0 vs. 2.1±0.9, P=0.02) on the geriatric population than in the nongeriatric of female MS patients. Conclusions: Geriatric population of MS has few differences of urinary disorders compared to a nongeriatric population with EDSS, sex, and MS form equal. However, the psychological impact of these urinary disorders is less important in female geriatric population.
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참고문헌 (26)
참고문헌 신청
Leray E / 2015 / Excess mortality in patients with multiple sclerosis starts at 20 years from clinical onset: data from a large-scale French observational study / PLoS One 10:e0132033
Buhse M / 2015 / The elderly person with multiple sclerosis: clinical implications for the increasing life-span / J Neurosci Nurs 47:333~339
Stern M / 2005 / Aging with multiple sclerosis / Phys Med Rehabil Clin N Am 16:219~234
Wiedemann A / 2013 / Which clinical risk factors determine a pathological urodynamic evaluation in patients with multiple sclerosis? an analysis of 100 prospective cases / World J Urol 31:229~233
Wang T / 2016 / Clinical characteristics and urodynamic analysis of urinary dysfunction in multiple sclerosis / Chin Med J (Engl) 129:645~650
Buhse M / 2015 / The elderly person with multiple sclerosis: clinical implications for the increasing life-span / J Neurosci Nurs 47:333~339
Stern M / 2005 / Aging with multiple sclerosis / Phys Med Rehabil Clin N Am 16:219~234
Wiedemann A / 2013 / Which clinical risk factors determine a pathological urodynamic evaluation in patients with multiple sclerosis? an analysis of 100 prospective cases / World J Urol 31:229~233
Wang T / 2016 / Clinical characteristics and urodynamic analysis of urinary dysfunction in multiple sclerosis / Chin Med J (Engl) 129:645~650
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