지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 1,063 - 1,069 (7page)
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Purpose: To investigate associations between dyspnea and clinical outcomes in patients with non-small cell lung cancer (NSCLC).
Materials and Methods: From 2001 to 2014, we retrospectively reviewed the prospective lung cancer database of St. Paul’s Hospitalat the Catholic University of Korea. We enrolled patients with NSCLC and evaluated symptoms of dyspnea using modified Medical Research Council (mMRC) scores. Also, we estimated pulmonary functions and analyzed survival data.
Results: In total, 457 NSCLC patients were enrolled, and 259 (56.7%) had dyspnea. Among those with dyspnea and whose mMRC scores were available (109 patients had no mMRC score), 85 (56.6%) patients had an mMRC score <2, while 65 (43.3%) had an mMRC score ≥2. Significant decreased pulmonary functions were observed in patients with dyspnea. In multivariate analysis, aging,poor performance status, advanced stage, low forced expiratory volume in 1 second (%), and an mMRC score ≥2 were found to be significant prognostic factors for patient survival.
Conclusion: Dyspnea could be a significant prognostic factor in patients with NSCLC.
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참고문헌 (23)
참고문헌 신청
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National Lung Screening Trial Research Team / 2011 / Reduced lung-cancer mortality with low-dose computed tomographic screening / N Engl J Med 365:395~409
Walters S / 2013 / Lung cancer survival and stage at diagnosis in Australia, Canada, Denmark, Norway, Sweden and the UK: a population-based study, 2004-2007 / Thorax 68:551~564
Carlson LE / 2013 / Screening for distress, the sixth vital sign, in lung cancer patients: effects on pain, fatigue, and common problems--secondary outcomes of a randomized controlled trial / Psychooncology 22:1880~1888
Luengo-Fernandez R / 2013 / Economic burden of cancer across the European Union: a population-based cost analysis / Lancet Oncol 14:1165~1174
National Lung Screening Trial Research Team / 2011 / Reduced lung-cancer mortality with low-dose computed tomographic screening / N Engl J Med 365:395~409
Walters S / 2013 / Lung cancer survival and stage at diagnosis in Australia, Canada, Denmark, Norway, Sweden and the UK: a population-based study, 2004-2007 / Thorax 68:551~564
Carlson LE / 2013 / Screening for distress, the sixth vital sign, in lung cancer patients: effects on pain, fatigue, and common problems--secondary outcomes of a randomized controlled trial / Psychooncology 22:1880~1888
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