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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2004.1
- 수록면
- 1 - 4 (4page)
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초록· 키워드
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Specialized clinical cell processing began in the Department of Transfusion Medicine at the National Institutes of Health in 1984. The number and complexity of procedures performed increased quickly and in 1997 a highly specialized cell processing laboratory was opened. The laboratory has approximately 3,000 square feet, specialized air handing, a highly trained staff, and written laboratory procedures. In addition to standard laboratory equipment, the laboratory has numerous cell isolation instruments, flow cytometers, and automated cell counting instruments. The laboratory supports blood and bone marrow transplant protocols by isolating CD34+ stem cells, removing T lymphocytes, culturing lymphocytes to eliminate donor lymphocytes that are reactive with recipient alloantigens, and stimulating lymphocytes to induce Th2 type cells to reduce graft versus host disease. The laboratory has also been preparing dendritic cells to support protocols using immune therapy to treat cancer. In addition, pancreatic islet cells are isolated from organ donors for transplantation to treat type I diabetes mellitus.
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참고문헌 (11)
참고문헌 신청
/ 1996 / Quality assurance for cell processing: no more blind faith 36 : 1 ~ 4
/ 1998 / T cell-depleted bone marrow transplantation and delayed T cell add-back to control acute GVHD and conserve a graft-versus-leukemia effect 21 : 543 ~ 551
/ 2001 / Development of a clinical-scale method for generation of dendritic cells from PBMC for use in cancer immunotherapy 3 : 19 ~ 29
/ 2002 / Development of a closed-system process for clinical-scale generation of DCs: evaluation of two monocyte-enrichment methods and two culture containers 4 : 65 ~ 76
/ 2002 / Isolation of pancreatic islets for transplantation in type I diabetes. In: Sacher RA, editor. Cellular Therapy: New Frontiers in Transfusion Medicine : 45 ~ 76
/ 1998 / T cell-depleted bone marrow transplantation and delayed T cell add-back to control acute GVHD and conserve a graft-versus-leukemia effect 21 : 543 ~ 551
/ 2001 / Development of a clinical-scale method for generation of dendritic cells from PBMC for use in cancer immunotherapy 3 : 19 ~ 29
/ 2002 / Development of a closed-system process for clinical-scale generation of DCs: evaluation of two monocyte-enrichment methods and two culture containers 4 : 65 ~ 76
/ 2002 / Isolation of pancreatic islets for transplantation in type I diabetes. In: Sacher RA, editor. Cellular Therapy: New Frontiers in Transfusion Medicine : 45 ~ 76
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