지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 48 - 54 (7page)
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초록· 키워드
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Purpose: The purpose of this study was to evaluate the biodegradation and biocompatibility of poly L-lactic acid (PLLA) implantable mesh under in vitro and in vivo conditions.
Methods: PLLA mesh was examined for changes in weight and tensile strength. The histology of the tissue around the PLLA implant was also evaluated.
Results: The weight and tensile strength of the PLLA prosthesis was stable for 180 days. In addition, the surface of the PLLA mesh was not digested under in vitro or in vivo conditions as determined by scanning electron microscope. Histologically, there were no significant changes in the diameters of implanted PLLA mesh and subtype fibers over the course of 180 days.
Likewise, there were no significant changes in the number of inflammatory and mast cells after 180 days, nor was there an increase in the percentage of collagen surrounding the PLLA mesh.
Conclusions: The results indicate that PLLA prostheses have good rigidity and biocompatibility in vivo and in vitro.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Athanasiou KA / 1996 / Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers / Biomaterials 17 : 93 ~ 102
Bello YM / 2001 / Tissue-engineered skin. Current status in wound healing / Am J Clin Dermatol 2 : 305 ~ 313
Cobb WS / 2006 / Textile analysis of heavy weight, mid-weight, and light weight polypropylene mesh in a porcine ventral hernia model / J Surg Res 136 : 1 ~ 7
Cooper ML / 1991 / In vivo optimization of a living dermal substitute employing cultured human fibroblasts on a biodegradable polyglycolic acid or polyglactin mesh / Biomater
Desai VB / 1987 / Marlex mesh prosthesis for massive vaginal vault prolapse / Int Surg 72 : 160 ~ 162
Bello YM / 2001 / Tissue-engineered skin. Current status in wound healing / Am J Clin Dermatol 2 : 305 ~ 313
Cobb WS / 2006 / Textile analysis of heavy weight, mid-weight, and light weight polypropylene mesh in a porcine ventral hernia model / J Surg Res 136 : 1 ~ 7
Cooper ML / 1991 / In vivo optimization of a living dermal substitute employing cultured human fibroblasts on a biodegradable polyglycolic acid or polyglactin mesh / Biomater
Desai VB / 1987 / Marlex mesh prosthesis for massive vaginal vault prolapse / Int Surg 72 : 160 ~ 162
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