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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 35 - 38 (4page)
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Purpose: The eighth American Joint Committee on Cancer staging system for breast cancer was recently published to more accurately predict the prognosis by adding biomarkers such as estrogen receptors, progesterone receptors, and human epidermal growth factor receptor 2. However, this system is very complicated and difficult to use by clinicians. The authors developed a program to aid in setting up the staging system and confirmed its usefulness by applying it to theoretical combinations and actual clinical data. Methods: The program was developed using the Microsoft Excel Macro. It was used for the anatomic, clinical and pathological prognostic staging of 588 theoretical combinations. The stages were also calculated the stages using 840 patients with breast cancer without carcinoma in situ or distant metastasis who did not undergo preoperative chemotherapy. Results: The anatomic, clinical and pathological prognostic stages were identical in 240 out of 588 theoretical combinations. In the actual patients’ data, stages IB and IIIB were more frequent in clinical and pathological prognostic stages than in the anatomic stage. The anatomic stage was similar to the clinical prognostic stage in 58.2% and to the pathological prognostic stage in 61.9% of patients. Oncotype DX changed the pathological prognostic stage in 2.1% of patients. Conclusion: We developed a program for the new American Joint Committee on Cancer staging system that will be useful for clinical prognostic prediction and large survival data analysis.
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참고문헌 (5)
참고문헌 신청
Amin MB / 2017 / AJCC Cancer Staging Manual / Springer
Updated breast chapter for 8th edition
Mittendorf EA / Updates to the 8th edition AJCC staging system for breast cancer
Hyams DM / 2017 / Selecting postoperative adjuvant systemic therapy for early stage breast cancer: a critical assessment of commercially available gene expression assays / J Surg Oncol 115:647~662
Giuliano AE / 2017 / Breast Cancer-Major changes in the American Joint Committee on Cancer eighth edition cancer staging manual / CA Cancer J Clin 67:290~303
Updated breast chapter for 8th edition
Mittendorf EA / Updates to the 8th edition AJCC staging system for breast cancer
Hyams DM / 2017 / Selecting postoperative adjuvant systemic therapy for early stage breast cancer: a critical assessment of commercially available gene expression assays / J Surg Oncol 115:647~662
Giuliano AE / 2017 / Breast Cancer-Major changes in the American Joint Committee on Cancer eighth edition cancer staging manual / CA Cancer J Clin 67:290~303
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