지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 108 - 113 (6page)
이용수
초록· 키워드
오류제보하기
The natural history of chronic hepatitis B (CHB) is complex and may run through different immune phases that may overlap. In particulars, the immune-tolerant phase is the most interesting and not as well understood as we thought. The concept of true immune tolerance have been under challenged from immunology points of view. The major international guidelines have not yet reached a consensus on the definition of the immune-tolerant phase. While positive hepatitis B e antigen (HBeAg), high serum hepatitis B virus (HBV) DNA and normal serum alanine aminotransferase (ALT) levels are the three key features of this phase, some guidelines also put age into consideration. A new nomenclature, Phase 1 or HBeAg-positive chronic HBV infection, is given by the latest European Association for the Study of the Liver (EASL) published in April 2017. While current guidelines advise against starting antiviral treatment for immune-tolerant CHB patients, some new data suggest treating such patients may reduce the risk of liver fibrosis progression and hepatocellular carcinoma.
목차
등록된 정보가 없습니다.
참고문헌 (39)
참고문헌 신청
Schweitzer A / 2015 / Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013 / Lancet 386:1546~1555
Trepo C / 2014 / Hepatitis B virus infection / Lancet 384:2053~2063
Terrault NA / 2016 / AASLD guidelines for treatment of chronic hepatitis B / Hepatology 63:261~283
Sarin SK / 2016 / Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update / Hepatol Int 10:1~98
Bertoletti A / 2016 / Adaptive immunity in HBV infection / J Hepatol 64(1 Suppl):S71~S83
Trepo C / 2014 / Hepatitis B virus infection / Lancet 384:2053~2063
Terrault NA / 2016 / AASLD guidelines for treatment of chronic hepatitis B / Hepatology 63:261~283
Sarin SK / 2016 / Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update / Hepatol Int 10:1~98
Bertoletti A / 2016 / Adaptive immunity in HBV infection / J Hepatol 64(1 Suppl):S71~S83
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Risk of hepatocellular carcinoma in untreated patients with chronic hepatitis B: Independent of HBeAg status?
Clinical and Molecular Hepatology
2021 .01
-
Letter regarding “Long-term prognosis and the need for histologic assessment of chronic hepatitis B in the serological immune-tolerant phase”
Clinical and Molecular Hepatology
2023 .04
-
Negligible risk of hepatocellular carcinoma in chronic hepatitis B patients in immune-tolerant phase: Myth or fact
Clinical and Molecular Hepatology
2021 .01
-
Is liver biopsy essential to identifying the immune tolerant phase of chronic hepatitis B?
Clinical and Molecular Hepatology
2023 .04
-
Correspondence on Letter regarding “Long-term prognosis and the need for histologic assessment of chronic hepatitis B in the serological immune tolerant phase”
Clinical and Molecular Hepatology
2023 .04
-
Hepatitis B Surface Antigen Quantification across Different Phases of Chronic Hepatitis B Virus Infection Using an Immunoradiometric Assay
Gut and Liver
2015 .01
-
Performance of Hepatitis B Core-Related Antigen Versus Hepatitis B Surface Antigen and Hepatitis B Virus DNA in Predicting HBeAg-positive and HBeAg-negative Chronic Hepatitis
Annals of Laboratory Medicine
2019 .01
-
The imitator of immune-tolerant chronic hepatitis B: A killer in disguise
Clinical and Molecular Hepatology
2023 .04
-
Immunotherapy for Chronic Hepatitis B Virus Infection
Gut and Liver
2018 .01
-
Postpartum Hepatic Flares in Immune-Tolerant Pregnant Patients with Chronic Hepatitis B Virus Infection
Gut and Liver
2022 .01
-
만성 B형간염 치료의 최신 지견: 2018 대한간학회 진료 가이드라인을 중심으로
대한내과학회지
2019 .06
-
만성 바이러스성 B형 간염 환자에서 HBeAg이 혈청전환된 1례
대한한방내과학회지
2016 .01
-
The Epidemiology of Hepatitis B Virus Infection in Korea: 15-Year Analysis
Journal of Korean Medical Science
2024 .01
-
Result Patterns and Characteristics of HBeAg and HBV DNA in Patients with Chronic Hepatitis B
Laboratory Medicine Online
2019 .01
-
Immune-mediated Liver Injury in Hepatitis B Virus Infection
Immune Network
2015 .08
-
Chronic Hepatitis C Virus Infection, Why Not Treat Now?
대한류마티스학회지
2018 .01
-
Comparison of clinical practice guidelines for the management of chronic hepatitis B: When to start, when to change, and when to stop
Clinical and Molecular Hepatology
2020 .01
-
Erectile dysfunction in patients with liver disease related to chronic hepatitis B
Clinical and Molecular Hepatology
2015 .01
-
만성 B형 및 C형 간염 환자의 간섬유화 진단을 위한 비침습적 혈액 표지자 평가
Laboratory Medicine Online
2019 .01
-
2017 KASL clinical practice guidelines management of hepatitis C: Treatment of chronic hepatitis C
Clinical and Molecular Hepatology
2018 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0